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Mining drug–target and drug–adverse drug reaction databases to identify target–adverse drug reaction relationships
The level of attrition on drug discovery, particularly at advanced stages, is very high due to unexpected adverse drug reactions (ADRs) caused by drug candidates, and thus, being able to predict undesirable responses when modulating certain protein targets would contribute to the development of safe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533369/ https://www.ncbi.nlm.nih.gov/pubmed/34679164 http://dx.doi.org/10.1093/database/baab068 |