Mevalonate Kinase Deficiency and Squalene Synthase Inhibitor (TAK-475): The Balance to Extinguish the Inflammation

Mevalonate Kinase Deficiency (MKD) is a rare inborn disease belonging to the family of periodic fever syndromes. The MKD phenotype is characterized by systemic inflammation involving multiple organs, including the nervous system. Current anti-inflammatory approaches to MKD are only partially effecti...

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Detalles Bibliográficos
Autores principales: Rimondi, Erika, Valencic, Erica, Tommasini, Alberto, Secchiero, Paola, Melloni, Elisabetta, Marcuzzi, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533390/
https://www.ncbi.nlm.nih.gov/pubmed/34680069
http://dx.doi.org/10.3390/biom11101438

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