Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis

Melanoma is an aggressive cancer characterized by the acidification of the extracellular environment. Here, we showed for the first time that extracellular media acidification increases proliferation, migration, and invasion of patient-derived metastatic melanoma cells and up-regulates cell-surface...

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Detalles Bibliográficos
Autores principales: Bychkov, Maxim L., Kirichenko, Artem V., Shulepko, Mikhail A., Mikhaylova, Irina N., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533404/
https://www.ncbi.nlm.nih.gov/pubmed/34680442
http://dx.doi.org/10.3390/biomedicines9101324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533404/
https://www.ncbi.nlm.nih.gov/pubmed/34680442
http://dx.doi.org/10.3390/biomedicines9101324

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