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Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering
Recent decades have seen a plethora of regenerating new tissues in order to treat a multitude of cardiovascular diseases. Autografts, xenografts and bioengineered extracellular matrices have been employed in this endeavor. However, current limitations of xenografts and exogenous scaffolds to acquire...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533407/ https://www.ncbi.nlm.nih.gov/pubmed/34677206 http://dx.doi.org/10.3390/bioengineering8100133 |
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author | Kozaniti, Foteini K. Metsiou, Despoina Nektaria Manara, Aikaterini E. Athanassiou, George Deligianni, Despina D. |
author_facet | Kozaniti, Foteini K. Metsiou, Despoina Nektaria Manara, Aikaterini E. Athanassiou, George Deligianni, Despina D. |
author_sort | Kozaniti, Foteini K. |
collection | PubMed |
description | Recent decades have seen a plethora of regenerating new tissues in order to treat a multitude of cardiovascular diseases. Autografts, xenografts and bioengineered extracellular matrices have been employed in this endeavor. However, current limitations of xenografts and exogenous scaffolds to acquire sustainable cell viability, anti-inflammatory and non-cytotoxic effects with anti-thrombogenic properties underline the requirement for alternative bioengineered scaffolds. Herein, we sought to encompass the methods of biofabricated scaffolds via 3D printing and bioprinting, the biomaterials and bioinks recruited to create biomimicked tissues of cardiac valves and vascular networks. Experimental and computational designing approaches have also been included. Moreover, the in vivo applications of the latest studies on the treatment of cardiovascular diseases have been compiled and rigorously discussed. |
format | Online Article Text |
id | pubmed-8533407 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85334072021-10-23 Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering Kozaniti, Foteini K. Metsiou, Despoina Nektaria Manara, Aikaterini E. Athanassiou, George Deligianni, Despina D. Bioengineering (Basel) Review Recent decades have seen a plethora of regenerating new tissues in order to treat a multitude of cardiovascular diseases. Autografts, xenografts and bioengineered extracellular matrices have been employed in this endeavor. However, current limitations of xenografts and exogenous scaffolds to acquire sustainable cell viability, anti-inflammatory and non-cytotoxic effects with anti-thrombogenic properties underline the requirement for alternative bioengineered scaffolds. Herein, we sought to encompass the methods of biofabricated scaffolds via 3D printing and bioprinting, the biomaterials and bioinks recruited to create biomimicked tissues of cardiac valves and vascular networks. Experimental and computational designing approaches have also been included. Moreover, the in vivo applications of the latest studies on the treatment of cardiovascular diseases have been compiled and rigorously discussed. MDPI 2021-09-27 /pmc/articles/PMC8533407/ /pubmed/34677206 http://dx.doi.org/10.3390/bioengineering8100133 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kozaniti, Foteini K. Metsiou, Despoina Nektaria Manara, Aikaterini E. Athanassiou, George Deligianni, Despina D. Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering |
title | Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering |
title_full | Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering |
title_fullStr | Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering |
title_full_unstemmed | Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering |
title_short | Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering |
title_sort | recent advancements in 3d printing and bioprinting methods for cardiovascular tissue engineering |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533407/ https://www.ncbi.nlm.nih.gov/pubmed/34677206 http://dx.doi.org/10.3390/bioengineering8100133 |
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