Cargando…

DNA End Joining: G0-ing to the Core

Humans have evolved a series of DNA double-strand break (DSB) repair pathways to efficiently and accurately rejoin nascently formed pairs of double-stranded DNA ends (DSEs). In G0/G1-phase cells, non-homologous end joining (NHEJ) and alternative end joining (A-EJ) operate to support covalent rejoini...

Descripción completa

Detalles Bibliográficos
Autores principales:	Frock, Richard L., Sadeghi, Cheyenne, Meng, Jodie, Wang, Jing L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533500/ https://www.ncbi.nlm.nih.gov/pubmed/34680120 http://dx.doi.org/10.3390/biom11101487

Ejemplares similares

The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer
por: Sishc, Brock J., et al.
Publicado: (2017)

Making Ends Meet: Repairing Breaks in Bacterial DNA by Non-Homologous End-Joining
por: Bowater, Richard, et al.
Publicado: (2006)

Microhomology-mediated end joining: new players join the team
por: Wang, Hailong, et al.
Publicado: (2017)

DNA Polymerase θ: A Unique Multifunctional End-Joining Machine
por: Black, Samuel J., et al.
Publicado: (2016)

Focus-ING on DNA Integrity: Implication of ING Proteins in Cell Cycle Regulation and DNA Repair Modulation
por: Archambeau, Jérôme, et al.
Publicado: (2019)

Nonhomologous DNA End Joining in Cell-Free Extracts
por: Sharma, Sheetal, et al.
Publicado: (2010)

The spatial organization of non-homologous end joining: From bridging to end joining
por: Ochi, Takashi, et al.
Publicado: (2014)

DNA polymerase beta participates in DNA End-joining
por: Ray, Sreerupa, et al.
Publicado: (2018)

Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining
por: Ochi, Takashi, et al.
Publicado: (2010)

Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining
por: Kukshal, Vandna, et al.
Publicado: (2015)

Structural basis of DNA polymerase θ mediated DNA end joining
por: Li, Chuxuan, et al.
Publicado: (2022)

DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?
por: Weterings, Eric, et al.
Publicado: (2007)

Mismatch discrimination and sequence bias during end-joining by DNA ligases
por: Bilotti, Katharina, et al.
Publicado: (2022)

Non-homologous end joining in class switch recombination: the beginning of the end
por: Kotnis, Ashwin, et al.
Publicado: (2008)

Unsolved mystery: the role of BRCA1 in DNA end-joining
por: Saha, Janapriya, et al.
Publicado: (2016)

Comparative analysis of the end-joining activity of several DNA ligases
por: Bauer, Robert J., et al.
Publicado: (2017)

DNA non-homologous end-joining enters the resection arena
por: Jeggo, Penny A., et al.
Publicado: (2017)

Canonical DNA non-homologous end-joining; capacity versus fidelity
por: Shibata, Atsushi, et al.
Publicado: (2020)

How to fix DNA breaks: new insights into the mechanism of non-homologous end joining
por: Vogt, Alex, et al.
Publicado: (2023)

Alternative Non-Homologous End-Joining: Error-Prone DNA Repair as Cancer’s Achilles’ Heel
por: Caracciolo, Daniele, et al.
Publicado: (2021)

Mechanism of Microhomology-Mediated End-Joining Promoted by Human DNA Polymerase Theta
por: Kent, Tatiana, et al.
Publicado: (2015)

Coincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining
por: Hendrickson, Cynthia L., et al.
Publicado: (2010)

Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?
por: Strande, Natasha Tiffany, et al.
Publicado: (2012)

Fish-Ing for Enhancers in the Heart
por: Parisi, Costantino, et al.
Publicado: (2021)

Biological Functions of the ING Proteins
por: Dantas, Arthur, et al.
Publicado: (2019)

ING Tumour Suppressors and ING Splice Variants as Coregulators of the Androgen Receptor Signalling in Prostate Cancer
por: Melekhova, Anna, et al.
Publicado: (2021)

Cooperative Assembly of a Protein-DNA Filament for Nonhomologous End Joining
por: Tsai, Chun J., et al.
Publicado: (2013)

Reconstitution of Mycobacterium marinum Nonhomologous DNA End Joining Pathway in Leishmania
por: Zhang, Wen-Wei, et al.
Publicado: (2022)

A Single XLF Dimer Bridges DNA Ends During Non-Homologous End Joining
por: Graham, Thomas G.W., et al.
Publicado: (2018)

Polθ promotes the repair of 5′-DNA-protein crosslinks by microhomology-mediated end-joining
por: Chandramouly, Gurushankar, et al.
Publicado: (2021)

Dynamics of Ku and bacterial non-homologous end-joining characterized using single DNA molecule analysis
por: Öz, Robin, et al.
Publicado: (2021)

Alternative end-joining in BCR gene rearrangements and translocations: Alternative end-joining in BCR gene rearrangements and translocations
por: Bai, Wanyu, et al.
Publicado: (2022)

Archibald Inglis
Publicado: (1889)

Mallet-ing
Publicado: (1860)

Inge Borghuis
por: Kiers, Bart
Publicado: (2020)

SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end‐joining
por: Manjunath, Meghana, et al.
Publicado: (2021)

ING Proteins: Tumour Suppressors or Oncoproteins
por: Jacquet, Karine, et al.
Publicado: (2021)

PHF6 promotes non‐homologous end joining and G2 checkpoint recovery
por: Warmerdam, Daniël O, et al.
Publicado: (2019)

Polymerase theta-helicase promotes end joining by stripping single-stranded DNA-binding proteins and bridging DNA ends
por: Schaub, Jeffrey M, et al.
Publicado: (2022)

The importance of DNAPKcs for blunt DNA end joining is magnified when XLF is weakened
por: Cisneros-Aguirre, Metztli, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jk0aieho49jrqp47vuig9hu8sa