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Sex Hormone-Binding Globulin (SHBG) in Cerebrospinal Fluid Does Not Discriminate between the Main FTLD Pathological Subtypes but Correlates with Cognitive Decline in FTLD Tauopathies

Biomarkers to discriminate the main pathologies underlying frontotemporal lobar degeneration (FTLD-Tau, FTLD-TDP) are lacking. Our previous FTLD cerebrospinal fluid (CSF) proteome study revealed that sex hormone-binding globulin (SHBG) was specifically increased in FTLD-Tau patients. Here we investi...

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Detalles Bibliográficos
Autores principales: del Campo, Marta, Pijnenburg, Yolande A. L., Chen-Plotkin, Alice, Irwin, David J., Grossman, Murray, Twaalfhoven, Harry A. M., Hu, William T., Meeter, Lieke H., van Swieten, John, Vermunt, Lisa, Martens, Frans, Heijboer, Annemieke C., Teunissen, Charlotte E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533538/
https://www.ncbi.nlm.nih.gov/pubmed/34680117
http://dx.doi.org/10.3390/biom11101484