Neutrophils Isolated from Septic Patients Exhibit Elevated Uptake of Vitamin C and Normal Intracellular Concentrations despite a Low Vitamin C Milieu

Vitamin C (ascorbate) plays an important role in neutrophil function and is accumulated by the cells either directly via vitamin C transporters (SVCT) or indirectly following oxidation to dehydroascorbic acid. Septic patients are known to have significantly depleted plasma ascorbate status, but litt...

Descripción completa

Detalles Bibliográficos
Autores principales: Carr, Anitra C., Bozonet, Stephanie, Pullar, Juliet, Spencer, Emma, Rosengrave, Patrice, Shaw, Geoff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533547/
https://www.ncbi.nlm.nih.gov/pubmed/34679743
http://dx.doi.org/10.3390/antiox10101607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533547/
https://www.ncbi.nlm.nih.gov/pubmed/34679743
http://dx.doi.org/10.3390/antiox10101607

Ejemplares similares