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Neutrophils Isolated from Septic Patients Exhibit Elevated Uptake of Vitamin C and Normal Intracellular Concentrations despite a Low Vitamin C Milieu
Vitamin C (ascorbate) plays an important role in neutrophil function and is accumulated by the cells either directly via vitamin C transporters (SVCT) or indirectly following oxidation to dehydroascorbic acid. Septic patients are known to have significantly depleted plasma ascorbate status, but litt...
Autores principales: | Carr, Anitra C., Bozonet, Stephanie, Pullar, Juliet, Spencer, Emma, Rosengrave, Patrice, Shaw, Geoff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533547/ https://www.ncbi.nlm.nih.gov/pubmed/34679743 http://dx.doi.org/10.3390/antiox10101607 |
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