R-Score: A New Parameter to Assess the Quality of Variants’ Calls Assessed by NGS Using Liquid Biopsies

SIMPLE SUMMARY: Circulating tumor DNA profiling by next-generation sequencing (NGS) is becoming essential for guiding targeted therapies. However, it remains challenging. Here, we show that variant allele fraction and the median of absolute values of all pairwise differences impact the agreement bet...

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Detalles Bibliográficos
Autores principales: Serna-Blasco, Roberto, Sánchez-Herrero, Estela, Berrocal Renedo, María, Calabuig-Fariñas, Silvia, Molina-Vila, Miguel Ángel, Provencio, Mariano, Romero, Atocha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533561/
https://www.ncbi.nlm.nih.gov/pubmed/34681053
http://dx.doi.org/10.3390/biology10100954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533561/
https://www.ncbi.nlm.nih.gov/pubmed/34681053
http://dx.doi.org/10.3390/biology10100954

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