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R-Score: A New Parameter to Assess the Quality of Variants’ Calls Assessed by NGS Using Liquid Biopsies
SIMPLE SUMMARY: Circulating tumor DNA profiling by next-generation sequencing (NGS) is becoming essential for guiding targeted therapies. However, it remains challenging. Here, we show that variant allele fraction and the median of absolute values of all pairwise differences impact the agreement bet...
Autores principales: | Serna-Blasco, Roberto, Sánchez-Herrero, Estela, Berrocal Renedo, María, Calabuig-Fariñas, Silvia, Molina-Vila, Miguel Ángel, Provencio, Mariano, Romero, Atocha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533561/ https://www.ncbi.nlm.nih.gov/pubmed/34681053 http://dx.doi.org/10.3390/biology10100954 |
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