Cargando…

The NMD Pathway Regulates GABARAPL1 mRNA during the EMT

EMT is a reversible cellular process that is linked to gene expression reprogramming, which allows for epithelial cells to undergo a phenotypic switch to acquire mesenchymal properties. EMT is associated with cancer progression and cancer therapeutic resistance and it is known that, during the EMT,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baudu, Timothée, Parratte, Chloé, Perez, Valérie, Ancion, Marie, Millevoi, Stefania, Hervouet, Eric, Peigney, Anne, Peixoto, Paul, Overs, Alexis, Herfs, Michael, Fraichard, Annick, Guittaut, Michaël, Baguet, Aurélie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533616/ https://www.ncbi.nlm.nih.gov/pubmed/34680418 http://dx.doi.org/10.3390/biomedicines9101302

Ejemplares similares

GABARAPL1 Inhibits EMT Signaling through SMAD-Tageted Negative Feedback
por: Jacquet, Marine, et al.
Publicado: (2021)

The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models
por: Hervouet, Eric, et al.
Publicado: (2015)

Specific Distribution of the Autophagic Protein GABARAPL1/GEC1 in the Developing and Adult Mouse Brain and Identification of Neuronal Populations Expressing GABARAPL1/GEC1
por: Le Grand, Jaclyn Nicole, et al.
Publicado: (2013)

The ATG8 Family Proteins GABARAP and GABARAPL1 Target Antigen to Dendritic Cells to Prime CD4(+) and CD8(+) T Cells
por: Fonderflick, Leïla, et al.
Publicado: (2022)

GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF-7 breast cancer cells
por: Poillet-Perez, Laura, et al.
Publicado: (2017)

Epigenetic Regulation of EMT (Epithelial to Mesenchymal Transition) and Tumor Aggressiveness: A View on Paradoxical Roles of KDM6B and EZH2
por: Lachat, Camille, et al.
Publicado: (2018)

EMT is associated with an epigenetic signature of ECM remodeling genes
por: Peixoto, Paul, et al.
Publicado: (2019)

High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer
por: Berthier, A, et al.
Publicado: (2010)

The exon junction complex core factor eIF4A3 is a key regulator of HPV16 gene expression
por: Meznad, Koceila, et al.
Publicado: (2021)

EZH2 and KDM6B Expressions Are Associated with Specific Epigenetic Signatures during EMT in Non Small Cell Lung Carcinomas
por: Lachat, Camille, et al.
Publicado: (2020)

Epigenetic Control of Autophagy in Cancer Cells: A Key Process for Cancer-Related Phenotypes
por: Peixoto, Paul, et al.
Publicado: (2019)

A new crystal form of GABARAPL2
por: Scicluna, Kristen, et al.
Publicado: (2021)

Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma
por: Hervouet, Eric, et al.
Publicado: (2018)

The Fate of Th17 Cells is Shaped by Epigenetic Modifications and Remodeled by the Tumor Microenvironment
por: Renaude, Elodie, et al.
Publicado: (2020)

Autophagy is associated with a robust specific transcriptional signature in breast cancer subtypes
por: Grandvallet, Céline, et al.
Publicado: (2020)

Elucidation of the Mechanism of Host NMD Suppression by HTLV-1 Rex: Dissection of Rex to Identify the NMD Inhibitory Domain
por: Nakano, Kazumi, et al.
Publicado: (2022)

ATG9A Is Overexpressed in Triple Negative Breast Cancer and Its In Vitro Extinction Leads to the Inhibition of Pro-Cancer Phenotypes
por: Claude-Taupin, Aurore, et al.
Publicado: (2018)

A regulated NMD mouse model supports NMD inhibition as a viable therapeutic option to treat genetic diseases
por: Echols, Josh, et al.
Publicado: (2020)

NMD monitors translational fidelity 24/7
por: Celik, Alper, et al.
Publicado: (2017)

Environmental stresses suppress nonsense-mediated mRNA decay (NMD) and affect cells by stabilizing NMD-targeted gene expression
por: Usuki, Fusako, et al.
Publicado: (2019)

Autophagic Network Analysis of the Dual Effect of Sevoflurane on Neurons Associated with GABARAPL1 and 2
por: Lu, Guolin, et al.
Publicado: (2020)

Proximity Ligation In situ Assay is a Powerful Tool to Monitor Specific ATG Protein Interactions following Autophagy Induction
por: Gauthier, Thierry, et al.
Publicado: (2015)

Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies
por: Durand, Sébastien, et al.
Publicado: (2007)

The salicylic acid dependent and independent effects of NMD in plants
por: Rayson, Samantha, et al.
Publicado: (2012)

Human NMD ensues independently of stable ribosome stalling
por: Karousis, Evangelos D., et al.
Publicado: (2020)

The detection of specific hypermethylated WIF1 and NPY genes in circulating DNA by crystal digital PCR™ is a powerful new tool for colorectal cancer diagnosis and screening
por: Overs, Alexis, et al.
Publicado: (2021)

GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer
por: Su, Wei, et al.
Publicado: (2016)

Loss of GABARAPL1 confers ferroptosis resistance to cancer stem‐like cells in hepatocellular carcinoma
por: Du, Xiaojing, et al.
Publicado: (2022)

Insulin Inhibits Autophagy by Inhibiting the Binding of FoXO1 to the Promoter Region of GABARAPL1
por: Hong, Tao, et al.
Publicado: (2023)

Comparative RNA sequencing reveals that HPV16 E6 abrogates the effect of E6*I on ROS metabolism
por: Paget-Bailly, Philippe, et al.
Publicado: (2019)

The Immune System GTPase GIMAP6 Interacts with the Atg8 Homologue GABARAPL2 and Is Recruited to Autophagosomes
por: Pascall, John C., et al.
Publicado: (2013)

Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1
por: Keulers, Tom G., et al.
Publicado: (2021)

Correction: Insulin Inhibits Autophagy by Inhibiting the Binding of FoXO1 to the Promoter Region of GABARAPL1
por: Hong, Tao, et al.
Publicado: (2023)

Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe
por: Wen, Jikai, et al.
Publicado: (2010)

Large-Scale Evidence for Conservation of NMD Candidature Across Mammals
por: de Lima Morais, David A., et al.
Publicado: (2010)

Longevity regulation by NMD-mediated mRNA quality control
por: Son, Heehwa G., et al.
Publicado: (2017)

Selective destabilization of polypeptides synthesized from NMD-targeted transcripts
por: Chu, Vincent, et al.
Publicado: (2021)

MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1
por: Mo, Jianwen, et al.
Publicado: (2016)

GABARAPL1 acts as a potential marker and promotes tumor proliferation and metastasis in triple negative breast cancer
por: Ran, Li, et al.
Publicado: (2017)

Rapid induction of p62 and GABARAPL1 upon proteasome inhibition promotes survival before autophagy activation
por: Sha, Zhe, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gt9ulq0rf98i21gs3arldcra7o