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Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer

SIMPLE SUMMARY: Information about the relative length of patient stays, primary care, and prereferral intervals (from symptom onset to specialist referral) is very scarce, and how the presenting symptoms influence these intervals and referral routes remains unknown. This study assesses the impact of...

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Autores principales: Varela-Centelles, Pablo Ignacio, López, Daniel Pérez, López-Cedrún, José Luis, García-Rozado, Álvaro, Baz, Pablo Castelo, Romero-Méndez, Amparo, Seoane, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533728/
https://www.ncbi.nlm.nih.gov/pubmed/34680312
http://dx.doi.org/10.3390/cancers13205163
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author Varela-Centelles, Pablo Ignacio
López, Daniel Pérez
López-Cedrún, José Luis
García-Rozado, Álvaro
Baz, Pablo Castelo
Romero-Méndez, Amparo
Seoane, Juan
author_facet Varela-Centelles, Pablo Ignacio
López, Daniel Pérez
López-Cedrún, José Luis
García-Rozado, Álvaro
Baz, Pablo Castelo
Romero-Méndez, Amparo
Seoane, Juan
author_sort Varela-Centelles, Pablo Ignacio
collection PubMed
description SIMPLE SUMMARY: Information about the relative length of patient stays, primary care, and prereferral intervals (from symptom onset to specialist referral) is very scarce, and how the presenting symptoms influence these intervals and referral routes remains unknown. This study assesses the impact of presenting symptoms on time intervals, number of visits at the primary care level, and referral pattern of patients with symptomatic oral cancer. This approach will allow targets to be identified for future interventions and the optimization of the treatment pathway for symptomatic oral cancer patients. ABSTRACT: This investigation was aimed at determining the time intervals from the presenting symptoms until the beginning of oral cancer treatment and their relative contribution to the total time, and to assess the impact of the presenting symptom on diagnostic timelines and patient referral routes. A cross-sectional, ambispective study was designed to investigate symptomatic incident cases. The Aarhus statement was used as a conceptual framework. Strategies for minimizing potential recall biases were implemented. A sample of 181 patients was recruited (power: 99.5%; α = 0.05). The patient interval reached 58.2 days (95% CI, 40.3–76.2), which accounted for 74% of the whole prereferral interval and for more than one third of the total time interval. The presenting symptom (trigger for consultation) influenced both the number of primary care consultations and the length of time to diagnosis. General dental practitioners generated longer intervals to diagnosis (p < 0.005) and needed more consultations before referring a patient (RR = 0.76; 95% CI, 0.61–0.93), than general medical practitioners. The current study identifies the patient as the main target for interventions to improve awareness and reinforces the need for increased alertness amongst healthcare professionals about presenting symptoms of oral cancer and to diminish the number of prereferral consultations in order to optimize the primary care interval.
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spelling pubmed-85337282021-10-23 Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer Varela-Centelles, Pablo Ignacio López, Daniel Pérez López-Cedrún, José Luis García-Rozado, Álvaro Baz, Pablo Castelo Romero-Méndez, Amparo Seoane, Juan Cancers (Basel) Article SIMPLE SUMMARY: Information about the relative length of patient stays, primary care, and prereferral intervals (from symptom onset to specialist referral) is very scarce, and how the presenting symptoms influence these intervals and referral routes remains unknown. This study assesses the impact of presenting symptoms on time intervals, number of visits at the primary care level, and referral pattern of patients with symptomatic oral cancer. This approach will allow targets to be identified for future interventions and the optimization of the treatment pathway for symptomatic oral cancer patients. ABSTRACT: This investigation was aimed at determining the time intervals from the presenting symptoms until the beginning of oral cancer treatment and their relative contribution to the total time, and to assess the impact of the presenting symptom on diagnostic timelines and patient referral routes. A cross-sectional, ambispective study was designed to investigate symptomatic incident cases. The Aarhus statement was used as a conceptual framework. Strategies for minimizing potential recall biases were implemented. A sample of 181 patients was recruited (power: 99.5%; α = 0.05). The patient interval reached 58.2 days (95% CI, 40.3–76.2), which accounted for 74% of the whole prereferral interval and for more than one third of the total time interval. The presenting symptom (trigger for consultation) influenced both the number of primary care consultations and the length of time to diagnosis. General dental practitioners generated longer intervals to diagnosis (p < 0.005) and needed more consultations before referring a patient (RR = 0.76; 95% CI, 0.61–0.93), than general medical practitioners. The current study identifies the patient as the main target for interventions to improve awareness and reinforces the need for increased alertness amongst healthcare professionals about presenting symptoms of oral cancer and to diminish the number of prereferral consultations in order to optimize the primary care interval. MDPI 2021-10-14 /pmc/articles/PMC8533728/ /pubmed/34680312 http://dx.doi.org/10.3390/cancers13205163 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Varela-Centelles, Pablo Ignacio
López, Daniel Pérez
López-Cedrún, José Luis
García-Rozado, Álvaro
Baz, Pablo Castelo
Romero-Méndez, Amparo
Seoane, Juan
Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer
title Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer
title_full Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer
title_fullStr Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer
title_full_unstemmed Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer
title_short Impact of the Presenting Symptom on Time Intervals and Diagnostic Routes of Patients with Symptomatic Oral Cancer
title_sort impact of the presenting symptom on time intervals and diagnostic routes of patients with symptomatic oral cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533728/
https://www.ncbi.nlm.nih.gov/pubmed/34680312
http://dx.doi.org/10.3390/cancers13205163
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