ERK: A Double-Edged Sword in Cancer. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer

The RAF/MEK/ERK signaling pathway regulates diverse cellular processes as exemplified by cell proliferation, differentiation, motility, and survival. Activation of ERK1/2 generally promotes cell proliferation, and its deregulated activity is a hallmark of many cancers. Therefore, components and regu...

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Detalles Bibliográficos
Autores principales: Sugiura, Reiko, Satoh, Ryosuke, Takasaki, Teruaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533760/
https://www.ncbi.nlm.nih.gov/pubmed/34685488
http://dx.doi.org/10.3390/cells10102509

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