Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression

Mouse models of non-alcoholic fatty liver disease (NAFLD) are required to define therapeutic targets, but detailed time-resolved studies to establish a sequence of events are lacking. Here, we fed male C57Bl/6N mice a Western or standard diet over 48 weeks. Multiscale time-resolved characterization...

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Autores principales: Ghallab, Ahmed, Myllys, Maiju, Friebel, Adrian, Duda, Julia, Edlund, Karolina, Halilbasic, Emina, Vucur, Mihael, Hobloss, Zaynab, Brackhagen, Lisa, Begher-Tibbe, Brigitte, Hassan, Reham, Burke, Michael, Genc, Erhan, Frohwein, Lynn Johann, Hofmann, Ute, Holland, Christian H., González, Daniela, Keller, Magdalena, Seddek, Abdel-latif, Abbas, Tahany, Mohammed, Elsayed S. I., Teufel, Andreas, Itzel, Timo, Metzler, Sarah, Marchan, Rosemarie, Cadenas, Cristina, Watzl, Carsten, Nitsche, Michael A., Kappenberg, Franziska, Luedde, Tom, Longerich, Thomas, Rahnenführer, Jörg, Hoehme, Stefan, Trauner, Michael, Hengstler, Jan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533774/
https://www.ncbi.nlm.nih.gov/pubmed/34685496
http://dx.doi.org/10.3390/cells10102516

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