Impaired Bile Acid Metabolism and Gut Dysbiosis in Mice Lacking Lysosomal Acid Lipase

Lysosomal acid lipase (LAL) is the sole enzyme known to be responsible for the hydrolysis of cholesteryl esters and triglycerides at an acidic pH in lysosomes, resulting in the release of unesterified cholesterol and free fatty acids. However, the role of LAL in diet-induced adaptations is largely u...

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Detalles Bibliográficos
Autores principales: Sachdev, Vinay, Duta-Mare, Madalina, Korbelius, Melanie, Vujić, Nemanja, Leopold, Christina, Freark de Boer, Jan, Rainer, Silvia, Fickert, Peter, Kolb, Dagmar, Kuipers, Folkert, Radovic, Branislav, Gorkiewicz, Gregor, Kratky, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533808/
https://www.ncbi.nlm.nih.gov/pubmed/34685599
http://dx.doi.org/10.3390/cells10102619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533808/
https://www.ncbi.nlm.nih.gov/pubmed/34685599
http://dx.doi.org/10.3390/cells10102619

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