A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3

Spinocerebellar ataxia type 3 (SCA3) is a hereditary ataxia caused by inheritance of a mutated form of the human ATXN3 gene containing an expanded CAG repeat region, encoding a human ataxin-3 protein with a long polyglutamine (polyQ) repeat region. Previous studies have demonstrated that ataxin-3 co...

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Detalles Bibliográficos
Autores principales: Robinson, Katherine J., Yuan, Kristy, Plenderleith, Stuart K., Watchon, Maxinne, Laird, Angela S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533844/
https://www.ncbi.nlm.nih.gov/pubmed/34685571
http://dx.doi.org/10.3390/cells10102592

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