The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review

Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses. This review focuses on outlining the stimulatory as well as the inhibitory effects of heat-shock pr...

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Autores principales: Androvitsanea, Ariadni, Stylianou, Kostas, Drosataki, Eleni, Petrakis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533860/
https://www.ncbi.nlm.nih.gov/pubmed/34685607
http://dx.doi.org/10.3390/cells10102626
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author Androvitsanea, Ariadni
Stylianou, Kostas
Drosataki, Eleni
Petrakis, Ioannis
author_facet Androvitsanea, Ariadni
Stylianou, Kostas
Drosataki, Eleni
Petrakis, Ioannis
author_sort Androvitsanea, Ariadni
collection PubMed
description Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses. This review focuses on outlining the stimulatory as well as the inhibitory effects of heat-shock proteins 27, 40, 70, 65, 60, and 90 in experimental and clinical autoimmune settings.
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spelling pubmed-85338602021-10-23 The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review Androvitsanea, Ariadni Stylianou, Kostas Drosataki, Eleni Petrakis, Ioannis Cells Review Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses. This review focuses on outlining the stimulatory as well as the inhibitory effects of heat-shock proteins 27, 40, 70, 65, 60, and 90 in experimental and clinical autoimmune settings. MDPI 2021-10-01 /pmc/articles/PMC8533860/ /pubmed/34685607 http://dx.doi.org/10.3390/cells10102626 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Androvitsanea, Ariadni
Stylianou, Kostas
Drosataki, Eleni
Petrakis, Ioannis
The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review
title The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review
title_full The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review
title_fullStr The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review
title_full_unstemmed The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review
title_short The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review
title_sort pathophysiological role of heat shock response in autoimmunity: a literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533860/
https://www.ncbi.nlm.nih.gov/pubmed/34685607
http://dx.doi.org/10.3390/cells10102626
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