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Acquired Glucocorticoid Resistance Due to Homologous Glucocorticoid Receptor Downregulation: A Modern Look at an Age-Old Problem

For over 70 years, the unique anti-inflammatory properties of glucocorticoids (GCs), which mediate their effects via the ligand-activated transcription factor, the glucocorticoid receptor alpha (GRα), have allowed for the use of these steroid hormones in the treatment of various autoimmune and infla...

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Detalles Bibliográficos
Autores principales:	Spies, Lee-Maine L., Verhoog, Nicolette J. D., Louw, Ann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533966/ https://www.ncbi.nlm.nih.gov/pubmed/34685511 http://dx.doi.org/10.3390/cells10102529

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