Cargando…

Survival Is Related to Estrogen Signal Transduction Pathway Activity in Postmenopausal Women Diagnosed with High-Grade Serous Ovarian Carcinoma

SIMPLE SUMMARY: All cells have a complex internal network of ‘communication chains’ called signal transduction pathways (STPs). Through interaction of different proteins in STPs, they are partly responsible for the behavior of a cell. In our study, we investigated the activity of six STPs in 85 wome...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Lieshout, Laura, van der Ploeg, Phyllis, Wesseling-Rozendaal, Yvonne, van de Stolpe, Anja, Bosch, Steven, Lentjes-Beer, Marjolein, Ottenheijm, Meggy, Meriaan, Annelen, Vos, Caroline, de Hullu, Joanne, Massuger, Leon, Bekkers, Ruud, Piek, Jurgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533979/ https://www.ncbi.nlm.nih.gov/pubmed/34680250 http://dx.doi.org/10.3390/cancers13205101

Ejemplares similares

Functional estrogen receptor signaling pathway activity in high-grade serous ovarian carcinoma as compared to estrogen receptor protein expression by immunohistochemistry
por: van der Ploeg, Phyllis, et al.
Publicado: (2021)

Signal Transduction Pathway Activity in High-Grade, Serous Ovarian Carcinoma Reveals a More Favorable Prognosis in Tumors with Low PI3K and High NF-κB Pathway Activity: A Novel Approach to a Long-Standing Enigma
por: van Lieshout, Laura, et al.
Publicado: (2020)

Cyclic activity of signal transduction pathways in fimbrial epithelium of the human fallopian tube
por: van der Ploeg, Phyllis, et al.
Publicado: (2021)

Characterization of Immunoactive and Immunotolerant CD4+ T Cells in Breast Cancer by Measuring Activity of Signaling Pathways That Determine Immune Cell Function
por: Wesseling-Rozendaal, Yvonne, et al.
Publicado: (2022)

Adjuvant Hysterectomy for Cervical Cancer Patients Treated with Chemoradiation Therapy: A Systematic Review on the Pathology-Proven Residual Disease Rate
por: van Kol, Kim, et al.
Publicado: (2021)

The progression-free survival ratio as outcome measure in recurrent ovarian carcinoma patients: Current and future perspectives
por: van de Kruis, Nienke, et al.
Publicado: (2022)

Factors influencing decision-making around opportunistic salpingectomy: a nationwide survey
por: Steenbeek, Miranda P., et al.
Publicado: (2018)

Patients’ and professionals’ perspectives on implementation of opportunistic salpingectomy: a mixed-method study
por: Gelderblom, Malou E., et al.
Publicado: (2021)

Improved diagnosis of inflammatory bowel disease and prediction and monitoring of response to anti-TNF alpha treatment based on measurement of signal transduction pathway activity
por: Bouwman, Wilbert, et al.
Publicado: (2022)

Corrigendum: Improved diagnosis of inflammatory bowel disease and prediction and monitoring of response to anti-TNF alpha treatment based on measurement of signal transduction pathway activity
por: Bouwman, Wilbert, et al.
Publicado: (2023)

Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types
por: Stolpe, Anja van de, et al.
Publicado: (2019)

Exercise Programme in Endometrial Cancer; Protocol of the Feasibility and Acceptability Survivorship Trial (EPEC-FAST)
por: Smits, Anke, et al.
Publicado: (2015)

Intraperitoneal infusion of ex vivo-cultured allogeneic NK cells in recurrent ovarian carcinoma patients (a phase I study)
por: Hoogstad-van Evert, Janneke, et al.
Publicado: (2019)

Publisher Correction: Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types
por: van de Stolpe, Anja, et al.
Publicado: (2020)

Significant decrease of adenocarcinoma in situ not reflected in cervical adenocarcinoma incidence in the Netherlands 1989–2003
por: van de Nieuwenhof, H P, et al.
Publicado: (2008)

Patients with usual vulvar intraepithelial neoplasia-related vulvar cancer have an increased risk of cervical abnormalities
por: de Bie, R P, et al.
Publicado: (2009)

The efficacy of ultrasound in the follow up after a negative sentinel lymph node in women with vulvar cancer: a prospective single‐centre study
por: Pouwer, AW, et al.
Publicado: (2018)

Umbilical cord blood CD34(+) progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rg(null) mice
por: Hoogstad-van Evert, Janneke S., et al.
Publicado: (2017)

Peritoneal NK cells are responsive to IL-15 and percentages are correlated with outcome in advanced ovarian cancer patients
por: Hoogstad-van Evert, Janneke S., et al.
Publicado: (2018)

Impact of Sepsis on the Oncologic Outcomes of Advanced Epithelial Ovarian Cancer Patients: A Multicenter Observational Study
por: Said, Sherin A., et al.
Publicado: (2023)

Reflex cytology for triage of high‐risk human papillomavirus positive self‐sampled material in cervical cancer screening: a prospective cohort study
por: Loopik, DL, et al.
Publicado: (2020)

Adequacy of family history taking in ovarian cancer patients: a population-based study
por: van Altena, Anne M., et al.
Publicado: (2012)

Cervical intraepithelial neoplasia and the risk of spontaneous preterm birth: A Dutch population-based cohort study with 45,259 pregnancy outcomes
por: Loopik, Diede L., et al.
Publicado: (2021)

The incidence and management of shoulder complaints in general practice: a retrospective cohort study
por: van Doorn, Pieter F, et al.
Publicado: (2021)

Systemic adverse events in imiquimod use for cervical intraepithelial neoplasia – A case series
por: Wouters, Tirza, et al.
Publicado: (2019)

Salvage surgery for patients with residual disease after chemoradiation therapy for locally advanced cervical cancer: A systematic review on indication, complications, and survival
por: van Kol, Kim G. G., et al.
Publicado: (2021)

The use and safety of corticosteroid injections for shoulder pain in general practice: a retrospective cohort study
por: van Doorn, Pieter F, et al.
Publicado: (2021)

Development of the Patient’s Experience and Attitude Colposcopy Eindhoven Questionnaire (PEACE-q)
por: Pop, Victor J. M., et al.
Publicado: (2019)

The relative risk of noncervical high‐risk human papillomavirus‐related (pre)malignancies after recurrent cervical intraepithelial neoplasia grade 3: A population‐based study
por: Loopik, Diede L., et al.
Publicado: (2019)

Endometrial cancer prognosis in women with endometriosis and adenomyosis: A retrospective nationwide cohort study of 40 840 women
por: Hermens, Marjolein, et al.
Publicado: (2021)

Hemoglobin level predicts outcome for vulvar cancer patients independent of GLUT-1 and CA-IX expression in tumor tissue
por: van de Nieuwenhof, Hedwig P., et al.
Publicado: (2010)

Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways
por: van Wigcheren, Glenn F., et al.
Publicado: (2023)

Human Papillomavirus Persistence in Young Unscreened Women, a Prospective Cohort Study
por: Schmeink, Channa E., et al.
Publicado: (2011)

Quantitative Measurement of Functional Activity of the PI3K Signaling Pathway in Cancer
por: van de Stolpe, Anja
Publicado: (2019)

Surveillance of women at high risk for hereditary ovarian cancer is inefficient
por: Oei, A L, et al.
Publicado: (2006)

Endometrial Cancer Incidence in Endometriosis and Adenomyosis
por: Hermens, Marjolein, et al.
Publicado: (2021)

Daily sedentary time and physical activity as assessed by accelerometry and their correlates in older adults
por: van Ballegooijen, Adriana J., et al.
Publicado: (2019)

The emerging role of GATA transcription factors in development and disease
por: Lentjes, Marjolein HFM, et al.
Publicado: (2016)

Ovarian Cyst Fluid of Serous Ovarian Tumors Contains Large Quantities of the Brain Amino Acid N-acetylaspartate
por: Kolwijck, Eva, et al.
Publicado: (2010)

Risk factors for short- and long-term complications after groin surgery in vulvar cancer
por: Hinten, F, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_uu9ose99cfad2tvmjdg53dia2d