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Global Methylome Scores Correlate with Histological Subtypes of Colorectal Carcinoma and Show Different Associations with Common Clinical and Molecular Features

SIMPLE SUMMARY: Aberrant patterns of methylation at specific genome sequences (CpG) are driving forces for the carcinogenesis process of different cancers, including colorectal cancer (CRC) and, typically, include gene promoter hypermethylation and global genome hypomethylation. Despite that CRC is...

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Detalles Bibliográficos
Autores principales:	Turpín-Sevilla, María del Carmen, Pérez-Sanz, Fernando, García-Solano, José, Sebastián-León, Patricia, Trujillo-Santos, Javier, Carbonell, Pablo, Estrada, Eduardo, Tuomisto, Anne, Herruzo, Irene, Fennell, Lochlan J., Mäkinen, Markus J., Rodríguez-Braun, Edith, Whitehall, Vicki L. J., Conesa, Ana, Conesa-Zamora, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533997/ https://www.ncbi.nlm.nih.gov/pubmed/34680315 http://dx.doi.org/10.3390/cancers13205165

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