Cargando…

Deep Learning to Decipher the Progression and Morphology of Axonal Degeneration

Axonal degeneration (AxD) is a pathological hallmark of many neurodegenerative diseases. Deciphering the morphological patterns of AxD will help to understand the underlying mechanisms and develop effective therapies. Here, we evaluated the progression of AxD in cortical neurons using a novel microf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Palumbo, Alex, Grüning, Philipp, Landt, Svenja Kim, Heckmann, Lara Eleen, Bartram, Luisa, Pabst, Alessa, Flory, Charlotte, Ikhsan, Maulana, Pietsch, Sören, Schulz, Reinhard, Kren, Christopher, Koop, Norbert, Boltze, Johannes, Madany Mamlouk, Amir, Zille, Marietta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534012/ https://www.ncbi.nlm.nih.gov/pubmed/34685519 http://dx.doi.org/10.3390/cells10102539

Ejemplares similares

Neuronal Stem Cell and Drug Interactions: A Systematic Review and Meta‐Analysis: Concise Review
por: Ikhsan, Maulana, et al.
Publicado: (2019)

Approaches to quantify axonal morphology for the analysis of axonal degeneration
por: Palumbo, Alex, et al.
Publicado: (2022)

The impact of endothelial cell death in the brain and its role after stroke: A systematic review
por: Zille, Marietta, et al.
Publicado: (2019)

Pharmacologically targeting inflammation and improving cerebrospinal fluid circulation improves outcome after subarachnoid haemorrhage
por: Zille, Marietta, et al.
Publicado: (2022)

Potential effects of commonly applied drugs on neural stem cell proliferation and viability: A hypothesis-generating systematic review and meta-analysis
por: Mortimer, Katherine R. H., et al.
Publicado: (2022)

Self-organization of virtual odorant receptors inspired by insect olfaction
por: Mamlouk, Amir Madany, et al.
Publicado: (2011)

Sparse coding representation of emotional brain states in fMRI data
por: Mamlouk, Amir Madany, et al.
Publicado: (2010)

On the efficiency of the genetic code after frameshift mutations
por: Geyer, Regine, et al.
Publicado: (2018)

Novel targets, treatments, and advanced models for intracerebral haemorrhage
por: Zille, Marietta, et al.
Publicado: (2022)

Skin-Derived Stem Cells for Wound Treatment Using Cultured Epidermal Autografts: Clinical Applications and Challenges
por: Brockmann, Inga, et al.
Publicado: (2018)

Dimensional Complexity of the Resting Brain in Healthy Aging, Using a Normalized MPSE
por: Scheel, Norman, et al.
Publicado: (2018)

A Novel Validation Algorithm Allows for Automated Cell Tracking and the Extraction of Biologically Meaningful Parameters
por: Rapoport, Daniel H., et al.
Publicado: (2011)

Assessing medical students’ perceived stress levels by comparing a chatbot-based approach to the Perceived Stress Questionnaire (PSQ20) in a mixed-methods study
por: Moldt, Julia-Astrid, et al.
Publicado: (2022)

PhyloMap: an algorithm for visualizing relationships of large sequence data sets and its application to the influenza A virus genome
por: Zhang, Jiajie, et al.
Publicado: (2011)

Learning to Predict Ischemic Stroke Growth on Acute CT Perfusion Data by Interpolating Low-Dimensional Shape Representations
por: Lucas, Christian, et al.
Publicado: (2018)

Chatbots for future docs: exploring medical students’ attitudes and knowledge towards artificial intelligence and medical chatbots
por: Moldt, Julia-Astrid, et al.
Publicado: (2023)

Editorial: Innovative models of stroke pathology
por: Crilly, Siobhan, et al.
Publicado: (2023)

Deciphering the axonal transport kinetics of neurofilaments using the fluorescence photo-activation pulse-escape method
por: Li, Yinyun, et al.
Publicado: (2014)

Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects
por: Wegiel, Jarek, et al.
Publicado: (2018)

The Effect of Probiotic Lactobacillus acidophilus and Ethanolic Propolis Compound toward Nucleic Acid Deposition in the Extracellular Polymeric Substance of Root Canal Bacteria
por: Adiningrat, Arya, et al.
Publicado: (2022)

Editorial: Neurodegenerative Diseases: Looking Beyond the Boundaries of the Brain
por: Gutiérrez-Ospina, Gabriel, et al.
Publicado: (2022)

Olfactory discrimination largely persists in mice with defects in odorant receptor expression and axon guidance
por: Knott, Thomas K, et al.
Publicado: (2012)

Decipher
por: Pavlou, S
Publicado: (2001)

Decipher
Publicado: (2002)

Adaptive Gaze Behavior and Decision Making of Penalty Corner Strikers in Field Hockey
por: Klatt, Stefanie, et al.
Publicado: (2021)

Tracking axon initial segment plasticity using high-density microelectrode arrays: A computational study
por: Kumar, Sreedhar S., et al.
Publicado: (2022)

Join us on an amazing journey towards next‐generation treatments for CNS disorders: Launch of Neuroprotection, a new high‐quality journal in translational neuroscience
por: Ji, Xunming, et al.
Publicado: (2022)

Axon-Autonomous Effects of the Amyloid Precursor Protein Intracellular Domain (AICD) on Kinase Signaling and Fast Axonal Transport
por: König, Svenja, et al.
Publicado: (2023)

Glycosaminoglycans as Tools to Decipher the Platelet Tumor Cell Interaction: A Focus on P-Selectin
por: Schwarz, Svenja, et al.
Publicado: (2020)

A Novel Microphysiological Colon Platform to Decipher Mechanisms Driving Human Intestinal Permeability
por: Apostolou, Athanasia, et al.
Publicado: (2021)

The pig as a model for immunology research
por: Pabst, Reinhard
Publicado: (2020)

Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells—Deciphering Novel Potential Targets for a Cell Sensitization
por: Jakubzig, Bastian, et al.
Publicado: (2018)

Romanians decipher the Universe
por: Balan, Sorin
Publicado: (2007)

Deciphering the glycogenome of schistosomes
por: Mickum, Megan L., et al.
Publicado: (2014)

Deciphering Thymic Development
por: Von Boehmer, Harald
Publicado: (2014)

Deciphering cancer fibroblasts
por: Biffi, Giulia, et al.
Publicado: (2018)

Deciphering Streptococcal Biofilms
por: Yadav, Puja, et al.
Publicado: (2020)

Deciphering the Great Mimicker
por: Shih, Jerry J.
Publicado: (2021)

Materiales para ingeniería civil
por: Mamlouk, Michael S.
Publicado: (2009)

Coronary Sinus Reducing Stent for the Treatment of Refractory Angina Pectoris: A Health Technology Assessment
por: Stanak, Michal, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_uql7aolquh6n7vc24pgs3rd680