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The Flagellin:Allergen Fusion Protein rFlaA:Betv1 Induces a MyD88− and MAPK-Dependent Activation of Glucose Metabolism in Macrophages

TLR5 ligand flagellin-containing fusion proteins are potential vaccine candidates for many diseases. A recombinant fusion protein of flagellin A and the major birch pollen allergen Bet v 1 (rFlaA:Betv1) modulates immune responses in vitro and in vivo. We studied the effects of rFlaA:Betv1 on bone ma...

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Detalles Bibliográficos
Autores principales: Lin, Yen-Ju, Papp, Garibald, Miskey, Csaba, Fiedler, Anna, Goretzki, Alexandra, Wolfheimer, Sonja, Zimmermann, Jennifer, Crauwels, Peter, Ivics, Zoltán, van Zandbergen, Ger, Vieths, Stefan, Scheurer, Stephan, Schülke, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534024/
https://www.ncbi.nlm.nih.gov/pubmed/34685593
http://dx.doi.org/10.3390/cells10102614