The Roles of Diacylglycerol Kinase α in Cancer Cell Proliferation and Apoptosis

SIMPLE SUMMARY: Diacylglycerol (DG) kinase (DGK) phosphorylates DG to generate phosphatidic acid (PA). DGKα is highly expressed in several refractory cancer cells, including melanoma, hepatocellular carcinoma, and glioblastoma cells, attenuates apoptosis, and promotes proliferation. In cancer cells,...

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Detalles Bibliográficos
Autores principales: Sakane, Fumio, Hoshino, Fumi, Ebina, Masayuki, Sakai, Hiromichi, Takahashi, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534027/
https://www.ncbi.nlm.nih.gov/pubmed/34680338
http://dx.doi.org/10.3390/cancers13205190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534027/
https://www.ncbi.nlm.nih.gov/pubmed/34680338
http://dx.doi.org/10.3390/cancers13205190

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