Alternative Pre-mRNA Splicing of the Mu Opioid Receptor Gene, OPRM1: Insight into Complex Mu Opioid Actions

Most opioid analgesics used clinically, including morphine and fentanyl, as well as the recreational drug heroin, act primarily through the mu opioid receptor, a class A Rhodopsin-like G protein-coupled receptor (GPCR). The single-copy mu opioid receptor gene, OPRM1, undergoes extensive alternative...

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Detalles Bibliográficos
Autores principales: Liu, Shan, Kang, Wen-Jia, Abrimian, Anna, Xu, Jin, Cartegni, Luca, Majumdar, Susruta, Hesketh, Patrick, Bekker, Alex, Pan, Ying-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534031/
https://www.ncbi.nlm.nih.gov/pubmed/34680158
http://dx.doi.org/10.3390/biom11101525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534031/
https://www.ncbi.nlm.nih.gov/pubmed/34680158
http://dx.doi.org/10.3390/biom11101525

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