The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms

This review presents the main patterns of synthesis for theranostics platforms. We examine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranosti...

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Autores principales: Korolev, Dmitry, Postnov, Viktor, Aleksandrov, Ilia, Murin, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534059/
https://www.ncbi.nlm.nih.gov/pubmed/34680176
http://dx.doi.org/10.3390/biom11101544
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author Korolev, Dmitry
Postnov, Viktor
Aleksandrov, Ilia
Murin, Igor
author_facet Korolev, Dmitry
Postnov, Viktor
Aleksandrov, Ilia
Murin, Igor
author_sort Korolev, Dmitry
collection PubMed
description This review presents the main patterns of synthesis for theranostics platforms. We examine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of nanoparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.
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spelling pubmed-85340592021-10-23 The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms Korolev, Dmitry Postnov, Viktor Aleksandrov, Ilia Murin, Igor Biomolecules Review This review presents the main patterns of synthesis for theranostics platforms. We examine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of nanoparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine. MDPI 2021-10-19 /pmc/articles/PMC8534059/ /pubmed/34680176 http://dx.doi.org/10.3390/biom11101544 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Korolev, Dmitry
Postnov, Viktor
Aleksandrov, Ilia
Murin, Igor
The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms
title The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms
title_full The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms
title_fullStr The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms
title_full_unstemmed The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms
title_short The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms
title_sort combination of solid-state chemistry and medicinal chemistry as the basis for the synthesis of theranostics platforms
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534059/
https://www.ncbi.nlm.nih.gov/pubmed/34680176
http://dx.doi.org/10.3390/biom11101544
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