Cargando…

N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor Suppressor

N-myc downstream-regulated gene 2 (NDRG2) is a tumor suppressor gene that increases tumor sensitivity to anticancer drugs, slows tumor progression, and inhibits metastasis. NDRG2 is suppressed in various aggressive tumor positions, whereas NDRG2 expression is associated with patient prognosis, such...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Gayeon, Lim, Seyeon, Kim, Kwang Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534062/ https://www.ncbi.nlm.nih.gov/pubmed/34685629 http://dx.doi.org/10.3390/cells10102649

Ejemplares similares

The Function of N-Myc Downstream-Regulated Gene 2 (NDRG2) as a Negative Regulator in Tumor Cell Metastasis
por: Lee, Ki Won, et al.
Publicado: (2022)

Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancer
por: Hu, Wei, et al.
Publicado: (2015)

A Tumor Suppressor Gene, N-myc Downstream-Regulated Gene 1 (NDRG1), in Gliomas and Glioblastomas
por: Nakahara, Yukiko, et al.
Publicado: (2022)

N-myc downstream-regulated gene 2 (NDRG2) promoter methylation and expression in pituitary adenoma
por: Vaitkiene, Paulina, et al.
Publicado: (2017)

Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein
por: Kim, Kyung Rok, et al.
Publicado: (2020)

Expression profile of the N-myc Downstream Regulated Gene 2 (NDRG2) in human cancers with focus on breast cancer
por: Lorentzen, Anders, et al.
Publicado: (2011)

Overexpression of N-Myc Downstream-Regulated Gene 2 (NDRG2) Regulates the Proliferation and Invasion of Bladder Cancer Cells In Vitro and In Vivo
por: Li, Ruixiao, et al.
Publicado: (2013)

A Deletion in the N-Myc Downstream Regulated Gene 1 (NDRG1) Gene in Greyhounds with Polyneuropathy
por: Drögemüller, Cord, et al.
Publicado: (2010)

Oncogenic MNK signalling regulates the metastasis suppressor NDRG1
por: Tian, Shuye, et al.
Publicado: (2017)

N-myc downstream regulated gene 1 (ndrg1) functions as a molecular switch for cellular adaptation to hypoxia
por: Park, Jong S, et al.
Publicado: (2022)

NDRG2 Sensitizes Myeloid Leukemia to Arsenic Trioxide via GSK3β–NDRG2–PP2A Complex Formation
por: Park, Soojong, et al.
Publicado: (2019)

mTOR Regulation of N-Myc Downstream Regulated 1 (NDRG1) Phosphorylation in Clear Cell Renal Cell Carcinoma
por: Valluri, Anisha, et al.
Publicado: (2023)

A Gly98Val Mutation in the N-Myc Downstream Regulated Gene 1 (NDRG1) in Alaskan Malamutes with Polyneuropathy
por: Bruun, Camilla S., et al.
Publicado: (2013)

Clinical Diagnostic and Prognostic Potential of NDRG1 and NDRG2 in Hepatocellular Carcinoma Patients
por: Xu, Shaohua, et al.
Publicado: (2022)

Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression
por: Xu, Xinyuan, et al.
Publicado: (2015)

NDRG1 in Cancer: A Suppressor, Promoter, or Both?
por: Joshi, Vaibhavi, et al.
Publicado: (2022)

The metastasis suppressor NDRG1 directly regulates androgen receptor signaling in prostate cancer
por: Lim, Syer C., et al.
Publicado: (2021)

The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion
por: Sharma, Anup, et al.
Publicado: (2017)

N-myc Downstream-Regulated Gene 1 (NDRG1) Regulates Vascular Endothelial Growth Factor A (VEGFA) and Malignancies in Glioblastoma Multiforme (GBM)
por: Zhang, Xufan, et al.
Publicado: (2022)

The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1
por: Liu, Wensheng, et al.
Publicado: (2015)

CYLD Promotes Apoptosis of Nasopharyngeal Carcinoma Cells by Regulating NDRG1
por: Lin, Yanling, et al.
Publicado: (2020)

Retracted: N-myc Downstream-Regulated Gene 1 (NDRG1) Regulates Vascular Endothelial Growth Factor A (VEGFA) and Malignancies in Glioblastoma Multiforme (GBM)
por: International, BioMed Research
Publicado: (2023)

NDRG2 regulates adherens junction integrity to restrict colitis and tumourigenesis
por: Wei, Mengying, et al.
Publicado: (2020)

The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway
por: Wang, Jiabei, et al.
Publicado: (2014)

Expression of merlin, NDRG2, ERBB2, and c-MYC in meningiomas: relationship with tumor grade and recurrence
por: Ongaratti, B.R., et al.
Publicado: (2016)

NDRG2 as a marker protein for brain astrocytes
por: Flügge, Gabriele, et al.
Publicado: (2014)

N-myc Downstream Regulated Gene 1 (NDRG1) Promotes Metastasis of Human Scirrhous Gastric Cancer Cells through Epithelial Mesenchymal Transition
por: Ureshino, Hiroki, et al.
Publicado: (2012)

N-myc Downstream Regulated 1 (NDRG1) Is Regulated by Eukaryotic Initiation Factor 3a (eIF3a) during Cellular Stress Caused by Iron Depletion
por: Lane, Darius J. R., et al.
Publicado: (2013)

Regulation of tumor-associated macrophage (TAM) differentiation by NDRG2 expression in breast cancer cells
por: Lee, Soyeon, et al.
Publicado: (2022)

Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma
por: Lorentzen, Anders, et al.
Publicado: (2007)

NDRG2 inhibition of glycolysis in liver tumor cells is regulated by SIRT1
por: Zhang, Le, et al.
Publicado: (2023)

The Metastasis Suppressor, N-myc Downregulated Gene 1 (NDRG1), Is a Prognostic Biomarker for Human Colorectal Cancer
por: Mao, Zhihai, et al.
Publicado: (2013)

NDRG1 is expressed in human granulosa cells: An implicative role of NDRG1 in the ovary
por: Nishigaki, Akemi, et al.
Publicado: (2022)

NDRG2 inhibition facilitates angiogenesis of hepatocellular carcinoma
por: Wang, Jianlong, et al.
Publicado: (2021)

Correction: N-myc Downstream Regulated 1 (NDRG1) Is Regulated by Eukaryotic Initiation Factor 3a (eIF3a) during Cellular Stress Caused by Iron Depletion
por: Lane, Darius J. R., et al.
Publicado: (2016)

Overexpressed MicroRNA-182 Promotes Proliferation and Invasion in Prostate Cancer PC-3 Cells by Down-Regulating N-myc Downstream Regulated Gene 1 (NDRG1)
por: Liu, Ranlu, et al.
Publicado: (2013)

NDRG2 Expression Decreases Tumor-Induced Osteoclast Differentiation by Down-regulating ICAM1 in Breast Cancer Cells
por: Kim, Bomi, et al.
Publicado: (2016)

NDRG2 contributes to cisplatin sensitivity through modulation of BAK-to-Mcl-1 ratio
por: Park, Soojong, et al.
Publicado: (2018)

N-MYC Downstream Regulated Gene 4 (NDRG4), a Frequent Downregulated Gene through DNA Hypermethylation, plays a Tumor Suppressive Role in Esophageal Adenocarcinoma
por: Cao, Longlong, et al.
Publicado: (2020)

NDRG2 Controls COX-2/PGE(2)-Mediated Breast Cancer Cell Migration and Invasion
por: Kim, Myung-Jin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2nm2cc5ltu5oohf3dnhrf4gd32