CDK1-Mediated Phosphorylation of BAG3 Promotes Mitotic Cell Shape Remodeling and the Molecular Assembly of Mitotic p62 Bodies

The cochaperone BCL2-associated athanogene 3 (BAG3), in complex with the heat shock protein HSPB8, facilitates mitotic rounding, spindle orientation, and proper abscission of daughter cells. BAG3 and HSPB8 mitotic functions implicate the sequestosome p62/SQSTM1, suggesting a role for protein quality...

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Detalles Bibliográficos
Autores principales: Luthold, Carole, Lambert, Herman, Guilbert, Solenn M., Rodrigue, Marc-Antoine, Fuchs, Margit, Varlet, Alice-Anaïs, Fradet-Turcotte, Amélie, Lavoie, Josée N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534064/
https://www.ncbi.nlm.nih.gov/pubmed/34685619
http://dx.doi.org/10.3390/cells10102638

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