Mitochondrial Permeability Transition Causes Mitochondrial Reactive Oxygen Species- and Caspase 3-Dependent Atrophy of Single Adult Mouse Skeletal Muscle Fibers

Elevated mitochondrial reactive oxygen species (mROS) and an increase in caspase-3 activity are established mechanisms that lead to skeletal muscle atrophy via the upregulation of protein degradation pathways. However, the mechanisms upstream of an increase in mROS and caspase-3 activity in conditio...

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Detalles Bibliográficos
Autores principales: Skinner, Sarah K., Solania, Angelo, Wolan, Dennis W., Cohen, Michael S., Ryan, Terence E., Hepple, Russell T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534155/
https://www.ncbi.nlm.nih.gov/pubmed/34685566
http://dx.doi.org/10.3390/cells10102586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534155/
https://www.ncbi.nlm.nih.gov/pubmed/34685566
http://dx.doi.org/10.3390/cells10102586

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