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Mitochondrial Permeability Transition Causes Mitochondrial Reactive Oxygen Species- and Caspase 3-Dependent Atrophy of Single Adult Mouse Skeletal Muscle Fibers
Elevated mitochondrial reactive oxygen species (mROS) and an increase in caspase-3 activity are established mechanisms that lead to skeletal muscle atrophy via the upregulation of protein degradation pathways. However, the mechanisms upstream of an increase in mROS and caspase-3 activity in conditio...
Autores principales: | Skinner, Sarah K., Solania, Angelo, Wolan, Dennis W., Cohen, Michael S., Ryan, Terence E., Hepple, Russell T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534155/ https://www.ncbi.nlm.nih.gov/pubmed/34685566 http://dx.doi.org/10.3390/cells10102586 |
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