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Progress on Ras/MAPK Signaling Research and Targeting in Blood and Solid Cancers

SIMPLE SUMMARY: The Ras-Raf-MEK-ERK signaling pathway is responsible for regulating cell proliferation, differentiation, and survival. Overexpression and overactivation of members within the signaling cascade have been observed in many solid and blood cancers. Research often focuses on targeting the...

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Detalles Bibliográficos
Autores principales: Dillon, Martha, Lopez, Antonio, Lin, Edward, Sales, Dominic, Perets, Ron, Jain, Pooja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534156/
https://www.ncbi.nlm.nih.gov/pubmed/34680208
http://dx.doi.org/10.3390/cancers13205059