Cargando…
Progress on Ras/MAPK Signaling Research and Targeting in Blood and Solid Cancers
SIMPLE SUMMARY: The Ras-Raf-MEK-ERK signaling pathway is responsible for regulating cell proliferation, differentiation, and survival. Overexpression and overactivation of members within the signaling cascade have been observed in many solid and blood cancers. Research often focuses on targeting the...
Autores principales: | Dillon, Martha, Lopez, Antonio, Lin, Edward, Sales, Dominic, Perets, Ron, Jain, Pooja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534156/ https://www.ncbi.nlm.nih.gov/pubmed/34680208 http://dx.doi.org/10.3390/cancers13205059 |
Ejemplares similares
-
Aurora kinase A interacts with H-Ras and potentiates Ras-MAPK signaling
por: Umstead, MaKendra, et al.
Publicado: (2017) -
Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis
por: Mittal, Suruchi, et al.
Publicado: (2009) -
H-Ras Nanocluster Stability Regulates the Magnitude of MAPK Signal Output
por: Rotblat, Barak, et al.
Publicado: (2010) -
Systemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAA
por: Schmid, Tobias, et al.
Publicado: (2015) -
Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway
por: Gillies, Taryn E, et al.
Publicado: (2020)