Cargando…
USP28: Oncogene or Tumor Suppressor? A Unifying Paradigm for Squamous Cell Carcinoma
Squamous cell carcinomas are therapeutically challenging tumor entities. Low response rates to radiotherapy and chemotherapy are commonly observed in squamous patients and, accordingly, the mortality rate is relatively high compared to other tumor entities. Recently, targeting USP28 has been emerged...
Autores principales: | Prieto-Garcia, Cristian, Tomašković, Ines, Shah, Varun Jayeshkumar, Dikic, Ivan, Diefenbacher, Markus |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534253/ https://www.ncbi.nlm.nih.gov/pubmed/34685632 http://dx.doi.org/10.3390/cells10102652 |
Ejemplares similares
-
Inhibition of USP28 overcomes Cisplatin-resistance of squamous tumors by suppression of the Fanconi anemia pathway
por: Prieto-Garcia, Cristian, et al.
Publicado: (2021) -
USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K
por: Prieto‐Garcia, Cristian, et al.
Publicado: (2022) -
Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells
por: Prieto‐Garcia, Cristian, et al.
Publicado: (2020) -
USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer
por: Maier, Carina R., et al.
Publicado: (2023) -
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma
por: Cao, Yu-Fei, et al.
Publicado: (2022)