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Maintenance of Type IV Secretion Function During Helicobacter pylori Infection in Mice

The Helicobacter pylori type IV secretion system (T4SS) encoded on the cag pathogenicity island (cagPAI) secretes the CagA oncoprotein and other effectors into the gastric epithelium. During murine infection, T4SS function is lost in an immune-dependent manner, typically as a result of in-frame reco...

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Detalles Bibliográficos
Autores principales: Skoog, Emma C., Martin, Miriam E., Barrozo, Roberto M., Hansen, Lori M., Cai, Lucy P., Lee, Seung-Joo, Benoun, Joseph M., McSorley, Stephen J., Solnick, Jay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534286/
https://www.ncbi.nlm.nih.gov/pubmed/33443133
http://dx.doi.org/10.1128/mBio.03147-20