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Epigenetic DNA Modifications Upregulate SPRY2 in Human Colorectal Cancers

Conventional wisdom is that Sprouty2 (SPRY2), a suppressor of Receptor Tyrosine Kinase (RTK) signaling, functions as a tumor suppressor and is downregulated in many solid tumors. We reported, for the first time, that increased expression of SPRY2 augments cancer phenotype and Epithelial-Mesenchymal-...

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Detalles Bibliográficos
Autores principales:	Stuckel, Alexei J., Zeng, Shuai, Lyu, Zhen, Zhang, Wei, Zhang, Xu, Dougherty, Urszula, Mustafi, Reba, Zhang, Qiong, Joshi, Trupti, Bissonnette, Marc, Choudhury, Samrat Roy, Khare, Sharad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534322/ https://www.ncbi.nlm.nih.gov/pubmed/34685612 http://dx.doi.org/10.3390/cells10102632

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