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Oxysterol 7-α Hydroxylase (CYP7B1) Attenuates Metabolic-Associated Fatty Liver Disease in Mice at Thermoneutrality

Ambient temperature is an important determinant of both the alternative bile acid synthesis pathway controlled by oxysterol 7-α hydroxylase (CYP7B1) and the progression of metabolic-associated fatty liver disease (MAFLD). Here, we investigated whether CYP7B1 is involved in the etiology of MAFLD unde...

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Detalles Bibliográficos
Autores principales: Evangelakos, Ioannis, Schwinge, Dorothee, Worthmann, Anna, John, Clara, Roeder, Niklas, Pertzborn, Paul, Behrens, Janina, Schramm, Christoph, Scheja, Ludger, Heeren, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534379/
https://www.ncbi.nlm.nih.gov/pubmed/34685636
http://dx.doi.org/10.3390/cells10102656