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Neutropenia and Large Granular Lymphocyte Leukemia: From Pathogenesis to Therapeutic Options

Large granular lymphocyte leukemia (LGLL) is a rare lymphoproliferative disorder characterized by the clonal expansion of cytotoxic T-LGL or NK cells. Chronic isolated neutropenia represents the clinical hallmark of the disease, being present in up to 80% of cases. New advances were made in the biol...

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Detalles Bibliográficos
Autores principales: Calabretto, Giulia, Teramo, Antonella, Barilà, Gregorio, Vicenzetto, Cristina, Gasparini, Vanessa Rebecca, Semenzato, Gianpietro, Zambello, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534439/
https://www.ncbi.nlm.nih.gov/pubmed/34685780
http://dx.doi.org/10.3390/cells10102800