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The Surgical Management of Proximal Femoral Metastases: A Narrative Review
The proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigatio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534449/ https://www.ncbi.nlm.nih.gov/pubmed/34677238 http://dx.doi.org/10.3390/curroncol28050320 |
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author | Axelrod, Daniel Gazendam, Aaron M. Ghert, Michelle |
author_facet | Axelrod, Daniel Gazendam, Aaron M. Ghert, Michelle |
author_sort | Axelrod, Daniel |
collection | PubMed |
description | The proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigations are required to ensure accurate diagnosis and prognosis. The goals of surgical management is to provide pain relief and return to function with a construct that provides stability to allow for immediate weightbearing. Current surgical treatment options include intramedullary nailing, hemiarthroplasty or total hip arthroplasty and endoprosthetic reconstructions. Oligometastatic renal cell carcinoma must be given special consideration as tumor resection and reconstruction has survival benefit. Both tumor and patient characteristics must be taken into account before deciding on the appropriate surgical intervention. |
format | Online Article Text |
id | pubmed-8534449 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85344492021-10-23 The Surgical Management of Proximal Femoral Metastases: A Narrative Review Axelrod, Daniel Gazendam, Aaron M. Ghert, Michelle Curr Oncol Commentary The proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigations are required to ensure accurate diagnosis and prognosis. The goals of surgical management is to provide pain relief and return to function with a construct that provides stability to allow for immediate weightbearing. Current surgical treatment options include intramedullary nailing, hemiarthroplasty or total hip arthroplasty and endoprosthetic reconstructions. Oligometastatic renal cell carcinoma must be given special consideration as tumor resection and reconstruction has survival benefit. Both tumor and patient characteristics must be taken into account before deciding on the appropriate surgical intervention. MDPI 2021-09-28 /pmc/articles/PMC8534449/ /pubmed/34677238 http://dx.doi.org/10.3390/curroncol28050320 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Commentary Axelrod, Daniel Gazendam, Aaron M. Ghert, Michelle The Surgical Management of Proximal Femoral Metastases: A Narrative Review |
title | The Surgical Management of Proximal Femoral Metastases: A Narrative Review |
title_full | The Surgical Management of Proximal Femoral Metastases: A Narrative Review |
title_fullStr | The Surgical Management of Proximal Femoral Metastases: A Narrative Review |
title_full_unstemmed | The Surgical Management of Proximal Femoral Metastases: A Narrative Review |
title_short | The Surgical Management of Proximal Femoral Metastases: A Narrative Review |
title_sort | surgical management of proximal femoral metastases: a narrative review |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534449/ https://www.ncbi.nlm.nih.gov/pubmed/34677238 http://dx.doi.org/10.3390/curroncol28050320 |
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