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The Surgical Management of Proximal Femoral Metastases: A Narrative Review

The proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigatio...

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Detalles Bibliográficos
Autores principales: Axelrod, Daniel, Gazendam, Aaron M., Ghert, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534449/
https://www.ncbi.nlm.nih.gov/pubmed/34677238
http://dx.doi.org/10.3390/curroncol28050320
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author Axelrod, Daniel
Gazendam, Aaron M.
Ghert, Michelle
author_facet Axelrod, Daniel
Gazendam, Aaron M.
Ghert, Michelle
author_sort Axelrod, Daniel
collection PubMed
description The proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigations are required to ensure accurate diagnosis and prognosis. The goals of surgical management is to provide pain relief and return to function with a construct that provides stability to allow for immediate weightbearing. Current surgical treatment options include intramedullary nailing, hemiarthroplasty or total hip arthroplasty and endoprosthetic reconstructions. Oligometastatic renal cell carcinoma must be given special consideration as tumor resection and reconstruction has survival benefit. Both tumor and patient characteristics must be taken into account before deciding on the appropriate surgical intervention.
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spelling pubmed-85344492021-10-23 The Surgical Management of Proximal Femoral Metastases: A Narrative Review Axelrod, Daniel Gazendam, Aaron M. Ghert, Michelle Curr Oncol Commentary The proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigations are required to ensure accurate diagnosis and prognosis. The goals of surgical management is to provide pain relief and return to function with a construct that provides stability to allow for immediate weightbearing. Current surgical treatment options include intramedullary nailing, hemiarthroplasty or total hip arthroplasty and endoprosthetic reconstructions. Oligometastatic renal cell carcinoma must be given special consideration as tumor resection and reconstruction has survival benefit. Both tumor and patient characteristics must be taken into account before deciding on the appropriate surgical intervention. MDPI 2021-09-28 /pmc/articles/PMC8534449/ /pubmed/34677238 http://dx.doi.org/10.3390/curroncol28050320 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Commentary
Axelrod, Daniel
Gazendam, Aaron M.
Ghert, Michelle
The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_full The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_fullStr The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_full_unstemmed The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_short The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_sort surgical management of proximal femoral metastases: a narrative review
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534449/
https://www.ncbi.nlm.nih.gov/pubmed/34677238
http://dx.doi.org/10.3390/curroncol28050320
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