Cargando…

Cisplatin Reduces the Frequencies of Radiotherapy-Induced Micronuclei in Peripheral Blood Lymphocytes of Patients with Gynaecological Cancer: Possible Implications for the Risk of Second Malignant Neoplasms

Gynaecologic cancers are common among women and treatment includes surgery, radiotherapy or chemotherapy, where the last two methods induce DNA damage in non-targeted cells like peripheral blood lymphocytes (PBL). Damaged normal cells can transform leading to second malignant neoplasms (SMN) but the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Węgierek-Ciuk, Aneta, Lankoff, Anna, Lisowska, Halina, Kędzierawski, Piotr, Akuwudike, Pamela, Lundholm, Lovisa, Wojcik, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534481/ https://www.ncbi.nlm.nih.gov/pubmed/34685687 http://dx.doi.org/10.3390/cells10102709

Ejemplares similares

Comparative analysis of three functional predictive assays in lymphocytes of patients with breast and gynaecological cancer treated by radiotherapy
por: Padjas, Anna, et al.
Publicado: (2012)

Hypothermia differentially modulates the formation and decay of NBS1, γH2AX and 53BP1 foci in U2OS cells exposed to gamma radiation
por: Płódowska, Magdalena, et al.
Publicado: (2022)

Impact of fractionated cisplatin and radiation treatment on cell growth and accumulation of DNA damage in two normal cell types differing in origin
por: Akuwudike, Pamela, et al.
Publicado: (2023)

The DNA damage response to radiological imaging: from ROS and γH2AX foci induction to gene expression responses in vivo
por: López-Riego, Milagrosa, et al.
Publicado: (2023)

Biological effectiveness of very high gamma dose rate and its implication for radiological protection
por: Olofsson, Dante, et al.
Publicado: (2020)

Coralyne Radiosensitizes A549 Cells by Upregulation of CDKN1A Expression to Attenuate Radiation Induced G2/M Block of the Cell Cycle
por: Węgierek-Ciuk, Aneta, et al.
Publicado: (2021)

A comparative analysis of in vitro toxicity of diesel exhaust particles from combustion of 1st- and 2nd-generation biodiesel fuels in relation to their physicochemical properties—the FuelHealth project
por: Lankoff, Anna, et al.
Publicado: (2017)

Effects of Saponins against Clinical E. coli Strains and Eukaryotic Cell Line
por: Arabski, Michał, et al.
Publicado: (2012)

Targeted Radionuclide Therapy of Prostate Cancer—From Basic Research to Clinical Perspectives
por: Czerwińska, Malwina, et al.
Publicado: (2020)

Cell Type-Specific Patterns in the Accumulation of DNA Damage Following Multifractional Radiation Exposure
por: Akuwudike, Pamela, et al.
Publicado: (2022)

Impact of ATM and DNA-PK Inhibition on Gene Expression and Individual Response of Human Lymphocytes to Mixed Beams of Alpha Particles and X-Rays
por: Cheng, Lei, et al.
Publicado: (2019)

Genotoxic potential of diesel exhaust particles from the combustion of first- and second-generation biodiesel fuels—the FuelHealth project
por: Kowalska, Magdalena, et al.
Publicado: (2017)

Simultaneous induction of dispersed and clustered DNA lesions compromises DNA damage response in human peripheral blood lymphocytes
por: Cheng, Lei, et al.
Publicado: (2018)

Analysis of the Applicability of microRNAs in Peripheral Blood Leukocytes as Biomarkers of Sensitivity and Exposure to Fractionated Radiotherapy towards Breast Cancer
por: Marczyk, Michal, et al.
Publicado: (2021)

Selective cytotoxicity and antifungal properties of copper(II) and cobalt(II) complexes with imidazole-4-acetate anion or 1-allylimidazole
por: Gałczyńska, Katarzyna, et al.
Publicado: (2019)

Fluorescence in situ hybridisation for interphase chromosomal aberration-based biological dosimetry
por: Meher, Prabodha Kumar, et al.
Publicado: (2023)

Induction of Micronuclei in Cervical Cancer Treated with Radiotherapy
por: Kobayashi, Daijiro, et al.
Publicado: (2020)

Micronuclei versus Chromosomal Aberrations Induced by X-Ray in Radiosensitive Mammalian Cells
por: PLAMADEALA, Cristina, et al.
Publicado: (2015)

Alpha Radiation as a Way to Target Heterochromatic and Gamma Radiation-Exposed Breast Cancer Cells
por: Svetličič, Maja, et al.
Publicado: (2020)

Second Malignant Neoplasms Following Radiotherapy
por: Kumar, Sanath
Publicado: (2012)

The order of sequential exposure of U2OS cells to gamma and alpha radiation influences the formation and decay dynamics of NBS1 foci
por: Tartas, Adrianna, et al.
Publicado: (2023)

Live Dynamics of 53BP1 Foci Following Simultaneous Induction of Clustered and Dispersed DNA Damage in U2OS Cells
por: Sollazzo, Alice, et al.
Publicado: (2018)

HER2-positive breast cancer that resists therapeutic drugs and ionizing radiation releases sphingomyelin-based molecules to circulating blood serum
por: Monzen, Satoru, et al.
Publicado: (2020)

Neuroendocrine Neoplasms of the Gastrointestinal Tract versus Neuroendocrine Neoplasms of the Gynaecological Tract—Comparison of the Risk Factors and Non-Surgical Treatment Efficacy
por: Lorenz, Anna, et al.
Publicado: (2023)

The effect of lycopene supplementation on radiation-induced micronuclei in mice reticulocytes in vivo
por: Dobrzyńska, Małgorzata M., et al.
Publicado: (2019)

Could veterinarians be immune to contracting SARS-CoV-2?
por: Kozłowska-Geller, Monika Anna, et al.
Publicado: (2022)

Association of Radiotherapy for Rectal Cancer and Second Gynecological Malignant Neoplasms
por: Guan, Xu, et al.
Publicado: (2021)

No threshold dose for micronuclei induction?
por: Diehl-Marshall, I, et al.
Publicado: (1981)

Radiation-induced DNA damage and repair in human γδ and αβ T-lymphocytes analysed by the alkaline comet assay
por: Lisowska, Halina, et al.
Publicado: (2010)

CHROMOTHRIPSIS FROM DNA DAMAGE IN MICRONUCLEI
por: Zhang, Cheng-Zhong, et al.
Publicado: (2015)

Emergence of micronuclei as a genomic biomarker
por: Sabharwal, Robin, et al.
Publicado: (2015)

Micronuclei as a Predictor for Oral Carcinogenesis
por: Kiran, Kamini, et al.
Publicado: (2018)

Some Aspects of Radiotherapy in Relation to Gynæcology
por: King, J. B.
Publicado: (1933)

Role of radiotherapy and chemotherapy in the risk of second malignant neoplasms after cancer in childhood.
por: de Vathaire, F., et al.
Publicado: (1989)

Complex and Multifaceted Therapy-Related Myeloid Neoplasm Following Laryngeal Cancer Treated with Cisplatin and Radiotherapy
por: Niscola, Pasquale, et al.
Publicado: (2013)

DKK1 is a potential novel mediator of cisplatin-refractoriness in non-small cell lung cancer cell lines
por: Salim, Hogir, et al.
Publicado: (2015)

A MATLAB-based program for three-dimensional quantitative analysis of micronuclei reveals that neuroinflammation induces micronuclei formation in the brain
por: Yano, Sarasa, et al.
Publicado: (2021)

CHROMOSOME PULVERIZATION IN MICRONUCLEI INDUCED BY TRITIATED THYMIDINE
por: Ikeuchi, Tatsuro, et al.
Publicado: (1972)

Replication of somatic micronuclei in bovine enucleated oocytes
por: Canel, Natalia, et al.
Publicado: (2012)

Chromosomes trapped in micronuclei are liable to segregation errors
por: Soto, Mar, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8a21na20v1r4eatnbl7uj86n7l