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IQSEC2 Deficiency Results in Abnormal Social Behaviors Relevant to Autism by Affecting Functions of Neural Circuits in the Medial Prefrontal Cortex

IQSEC2 is a guanine nucleotide exchange factor (GEF) for ADP-ribosylation factor 6 (Arf6), of which protein is exclusively localized to the postsynaptic density of the excitatory synapse. Human genome studies have revealed that the IQSEC2 gene is associated with X-linked neurodevelopmental disorders...

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Detalles Bibliográficos
Autores principales:	Mehta, Anuradha, Shirai, Yoshinori, Kouyama-Suzuki, Emi, Zhou, Mengyun, Yoshizawa, Takahiro, Yanagawa, Toru, Mori, Takuma, Tabuchi, Katsuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534507/ https://www.ncbi.nlm.nih.gov/pubmed/34685703 http://dx.doi.org/10.3390/cells10102724

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