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Therapeutic Approaches for Patients with Cystic Fibrosis Not Eligible for Current CFTR Modulators
Cystic fibrosis is a severe autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene encoding the CFTR protein, a chloride channel expressed in many epithelial cells. New drugs called CFTR modulators aim at restoring the CFTR protein fun...
Autores principales: | Fajac, Isabelle, Sermet, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534516/ https://www.ncbi.nlm.nih.gov/pubmed/34685773 http://dx.doi.org/10.3390/cells10102793 |
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