Cargando…
Breast Cancer Surgery: New Issues
Since ancient times, breast cancer treatment has crucially relied on surgeons and clinicians making great efforts to find increasingly conservative approaches to cure the tumor. In the Halstedian era (mid-late 19th century), the predominant practice consisted of the radical and disfiguring removal o...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534635/ https://www.ncbi.nlm.nih.gov/pubmed/34677262 http://dx.doi.org/10.3390/curroncol28050344 |
_version_ | 1784587598928281600 |
---|---|
author | Magnoni, Francesca Alessandrini, Sofia Alberti, Luca Polizzi, Andrea Rotili, Anna Veronesi, Paolo Corso, Giovanni |
author_facet | Magnoni, Francesca Alessandrini, Sofia Alberti, Luca Polizzi, Andrea Rotili, Anna Veronesi, Paolo Corso, Giovanni |
author_sort | Magnoni, Francesca |
collection | PubMed |
description | Since ancient times, breast cancer treatment has crucially relied on surgeons and clinicians making great efforts to find increasingly conservative approaches to cure the tumor. In the Halstedian era (mid-late 19th century), the predominant practice consisted of the radical and disfiguring removal of the breast, much to the detriment of women’s psycho-physical well-being. Thanks to enlightened scientists such as Professor Umberto Veronesi, breast cancer surgery has since impressively progressed and adopted a much more conservative approach. Over the last three decades, a better understanding of tumor biology and of its significant biomarkers has made the assessment of genetic and molecular profiles increasingly important. At the same time, neo-adjuvant treatments have been introduced, and great improvements in genetics, imaging technologies and in both oncological and reconstructive surgical techniques have been made. The future of breast cancer management must now rest on an ever more precise and targeted type of surgery that, through an increasingly multidisciplinary and personalized approach, can ensure oncological radicality while offering the best possible quality of life. |
format | Online Article Text |
id | pubmed-8534635 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85346352021-10-23 Breast Cancer Surgery: New Issues Magnoni, Francesca Alessandrini, Sofia Alberti, Luca Polizzi, Andrea Rotili, Anna Veronesi, Paolo Corso, Giovanni Curr Oncol Review Since ancient times, breast cancer treatment has crucially relied on surgeons and clinicians making great efforts to find increasingly conservative approaches to cure the tumor. In the Halstedian era (mid-late 19th century), the predominant practice consisted of the radical and disfiguring removal of the breast, much to the detriment of women’s psycho-physical well-being. Thanks to enlightened scientists such as Professor Umberto Veronesi, breast cancer surgery has since impressively progressed and adopted a much more conservative approach. Over the last three decades, a better understanding of tumor biology and of its significant biomarkers has made the assessment of genetic and molecular profiles increasingly important. At the same time, neo-adjuvant treatments have been introduced, and great improvements in genetics, imaging technologies and in both oncological and reconstructive surgical techniques have been made. The future of breast cancer management must now rest on an ever more precise and targeted type of surgery that, through an increasingly multidisciplinary and personalized approach, can ensure oncological radicality while offering the best possible quality of life. MDPI 2021-10-11 /pmc/articles/PMC8534635/ /pubmed/34677262 http://dx.doi.org/10.3390/curroncol28050344 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Magnoni, Francesca Alessandrini, Sofia Alberti, Luca Polizzi, Andrea Rotili, Anna Veronesi, Paolo Corso, Giovanni Breast Cancer Surgery: New Issues |
title | Breast Cancer Surgery: New Issues |
title_full | Breast Cancer Surgery: New Issues |
title_fullStr | Breast Cancer Surgery: New Issues |
title_full_unstemmed | Breast Cancer Surgery: New Issues |
title_short | Breast Cancer Surgery: New Issues |
title_sort | breast cancer surgery: new issues |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534635/ https://www.ncbi.nlm.nih.gov/pubmed/34677262 http://dx.doi.org/10.3390/curroncol28050344 |
work_keys_str_mv | AT magnonifrancesca breastcancersurgerynewissues AT alessandrinisofia breastcancersurgerynewissues AT albertiluca breastcancersurgerynewissues AT polizziandrea breastcancersurgerynewissues AT rotilianna breastcancersurgerynewissues AT veronesipaolo breastcancersurgerynewissues AT corsogiovanni breastcancersurgerynewissues |