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Breast Cancer Surgery: New Issues

Since ancient times, breast cancer treatment has crucially relied on surgeons and clinicians making great efforts to find increasingly conservative approaches to cure the tumor. In the Halstedian era (mid-late 19th century), the predominant practice consisted of the radical and disfiguring removal o...

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Autores principales: Magnoni, Francesca, Alessandrini, Sofia, Alberti, Luca, Polizzi, Andrea, Rotili, Anna, Veronesi, Paolo, Corso, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534635/
https://www.ncbi.nlm.nih.gov/pubmed/34677262
http://dx.doi.org/10.3390/curroncol28050344
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author Magnoni, Francesca
Alessandrini, Sofia
Alberti, Luca
Polizzi, Andrea
Rotili, Anna
Veronesi, Paolo
Corso, Giovanni
author_facet Magnoni, Francesca
Alessandrini, Sofia
Alberti, Luca
Polizzi, Andrea
Rotili, Anna
Veronesi, Paolo
Corso, Giovanni
author_sort Magnoni, Francesca
collection PubMed
description Since ancient times, breast cancer treatment has crucially relied on surgeons and clinicians making great efforts to find increasingly conservative approaches to cure the tumor. In the Halstedian era (mid-late 19th century), the predominant practice consisted of the radical and disfiguring removal of the breast, much to the detriment of women’s psycho-physical well-being. Thanks to enlightened scientists such as Professor Umberto Veronesi, breast cancer surgery has since impressively progressed and adopted a much more conservative approach. Over the last three decades, a better understanding of tumor biology and of its significant biomarkers has made the assessment of genetic and molecular profiles increasingly important. At the same time, neo-adjuvant treatments have been introduced, and great improvements in genetics, imaging technologies and in both oncological and reconstructive surgical techniques have been made. The future of breast cancer management must now rest on an ever more precise and targeted type of surgery that, through an increasingly multidisciplinary and personalized approach, can ensure oncological radicality while offering the best possible quality of life.
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spelling pubmed-85346352021-10-23 Breast Cancer Surgery: New Issues Magnoni, Francesca Alessandrini, Sofia Alberti, Luca Polizzi, Andrea Rotili, Anna Veronesi, Paolo Corso, Giovanni Curr Oncol Review Since ancient times, breast cancer treatment has crucially relied on surgeons and clinicians making great efforts to find increasingly conservative approaches to cure the tumor. In the Halstedian era (mid-late 19th century), the predominant practice consisted of the radical and disfiguring removal of the breast, much to the detriment of women’s psycho-physical well-being. Thanks to enlightened scientists such as Professor Umberto Veronesi, breast cancer surgery has since impressively progressed and adopted a much more conservative approach. Over the last three decades, a better understanding of tumor biology and of its significant biomarkers has made the assessment of genetic and molecular profiles increasingly important. At the same time, neo-adjuvant treatments have been introduced, and great improvements in genetics, imaging technologies and in both oncological and reconstructive surgical techniques have been made. The future of breast cancer management must now rest on an ever more precise and targeted type of surgery that, through an increasingly multidisciplinary and personalized approach, can ensure oncological radicality while offering the best possible quality of life. MDPI 2021-10-11 /pmc/articles/PMC8534635/ /pubmed/34677262 http://dx.doi.org/10.3390/curroncol28050344 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Magnoni, Francesca
Alessandrini, Sofia
Alberti, Luca
Polizzi, Andrea
Rotili, Anna
Veronesi, Paolo
Corso, Giovanni
Breast Cancer Surgery: New Issues
title Breast Cancer Surgery: New Issues
title_full Breast Cancer Surgery: New Issues
title_fullStr Breast Cancer Surgery: New Issues
title_full_unstemmed Breast Cancer Surgery: New Issues
title_short Breast Cancer Surgery: New Issues
title_sort breast cancer surgery: new issues
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534635/
https://www.ncbi.nlm.nih.gov/pubmed/34677262
http://dx.doi.org/10.3390/curroncol28050344
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