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Hormonally Induced Hepatocellular Carcinoma in Diabetic Wild Type and Carbohydrate Responsive Element Binding Protein Knockout Mice

Objective: In the rat, the pancreatic islet transplantation model is an established method to induce hepatocellular carcinomas (HCC), due to insulin-mediated metabolic and molecular alterations like increased glycolysis and de novo lipogenesis and the oncogenic AKT/mTOR pathway including upregulatio...

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Detalles Bibliográficos
Autores principales:	Nuernberger, Vincent, Mortoga, Sharif, Metzendorf, Christoph, Burkert, Christian, Ehricke, Katrina, Knuth, Elisa, Zimmer, Jenny, Singer, Stephan, Nath, Neetika, Karim, Majedul, Yasser, Mohd, Calvisi, Diego F., Dombrowski, Frank, Ribback, Silvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534692/ https://www.ncbi.nlm.nih.gov/pubmed/34685767 http://dx.doi.org/10.3390/cells10102787

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