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Can AI Help Pediatricians? Diagnosing Kawasaki Disease Using DRSA

The DRSA method (dominance-based rough set approach) was used to create decision-making rules based on the results of physical examination and additional laboratory tests in the differential diagnosis of Kawasaki disease (KD), infectious mononucleosis and S. pyogenes pharyngitis in children. The stu...

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Autores principales: Siewert, Bartosz, Błaszczyński, Jerzy, Gowin, Ewelina, Słowiński, Roman, Wysocki, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534704/
https://www.ncbi.nlm.nih.gov/pubmed/34682194
http://dx.doi.org/10.3390/children8100929
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author Siewert, Bartosz
Błaszczyński, Jerzy
Gowin, Ewelina
Słowiński, Roman
Wysocki, Jacek
author_facet Siewert, Bartosz
Błaszczyński, Jerzy
Gowin, Ewelina
Słowiński, Roman
Wysocki, Jacek
author_sort Siewert, Bartosz
collection PubMed
description The DRSA method (dominance-based rough set approach) was used to create decision-making rules based on the results of physical examination and additional laboratory tests in the differential diagnosis of Kawasaki disease (KD), infectious mononucleosis and S. pyogenes pharyngitis in children. The study was conducted retrospectively. The search was based on the ICD-10 (International Classification of Diseases) codes of final diagnosis. Demographic and laboratory data from one Polish hospital (Poznan) were collected. Traditional statistical methods and the DRSA method were applied in data analysis. The algorithm formed 45 decision rules recognizing KD. The rules with the highest sensitivity (number of false negatives equals zero) were based on the presence of conjunctivitis and CRP (C-reactive Protein) ≥ 40.1 mg/L, thrombocytosis and ESR (Erythrocyte Sedimentation Rate) ≥ 77 mm/h; fair general condition and fever ≥ 5 days and rash; fair general condition and fever ≥ 5 days and conjunctivitis; fever ≥ 5 days and rash and CRP ≥ 7.05 mg/L. The DRSA analysis may be helpful in diagnosing KD at an early stage of the disease. It can be used even with a small amount of clinical or laboratory data.
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spelling pubmed-85347042021-10-23 Can AI Help Pediatricians? Diagnosing Kawasaki Disease Using DRSA Siewert, Bartosz Błaszczyński, Jerzy Gowin, Ewelina Słowiński, Roman Wysocki, Jacek Children (Basel) Article The DRSA method (dominance-based rough set approach) was used to create decision-making rules based on the results of physical examination and additional laboratory tests in the differential diagnosis of Kawasaki disease (KD), infectious mononucleosis and S. pyogenes pharyngitis in children. The study was conducted retrospectively. The search was based on the ICD-10 (International Classification of Diseases) codes of final diagnosis. Demographic and laboratory data from one Polish hospital (Poznan) were collected. Traditional statistical methods and the DRSA method were applied in data analysis. The algorithm formed 45 decision rules recognizing KD. The rules with the highest sensitivity (number of false negatives equals zero) were based on the presence of conjunctivitis and CRP (C-reactive Protein) ≥ 40.1 mg/L, thrombocytosis and ESR (Erythrocyte Sedimentation Rate) ≥ 77 mm/h; fair general condition and fever ≥ 5 days and rash; fair general condition and fever ≥ 5 days and conjunctivitis; fever ≥ 5 days and rash and CRP ≥ 7.05 mg/L. The DRSA analysis may be helpful in diagnosing KD at an early stage of the disease. It can be used even with a small amount of clinical or laboratory data. MDPI 2021-10-17 /pmc/articles/PMC8534704/ /pubmed/34682194 http://dx.doi.org/10.3390/children8100929 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Siewert, Bartosz
Błaszczyński, Jerzy
Gowin, Ewelina
Słowiński, Roman
Wysocki, Jacek
Can AI Help Pediatricians? Diagnosing Kawasaki Disease Using DRSA
title Can AI Help Pediatricians? Diagnosing Kawasaki Disease Using DRSA
title_full Can AI Help Pediatricians? Diagnosing Kawasaki Disease Using DRSA
title_fullStr Can AI Help Pediatricians? Diagnosing Kawasaki Disease Using DRSA
title_full_unstemmed Can AI Help Pediatricians? Diagnosing Kawasaki Disease Using DRSA
title_short Can AI Help Pediatricians? Diagnosing Kawasaki Disease Using DRSA
title_sort can ai help pediatricians? diagnosing kawasaki disease using drsa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534704/
https://www.ncbi.nlm.nih.gov/pubmed/34682194
http://dx.doi.org/10.3390/children8100929
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