Cargando…

A Complex Metabolic Network Confers Immunosuppressive Functions to Myeloid-Derived Suppressor Cells (MDSCs) within the Tumour Microenvironment

Myeloid-derived suppressor cells (MDSCs) constitute a plastic and heterogeneous cell population among immune cells within the tumour microenvironment (TME) that support cancer progression and resistance to therapy. During tumour progression, cancer cells modify their metabolism to sustain an increas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hofer, Francesca, Di Sario, Gianna, Musiu, Chiara, Sartoris, Silvia, De Sanctis, Francesco, Ugel, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534848/ https://www.ncbi.nlm.nih.gov/pubmed/34685679 http://dx.doi.org/10.3390/cells10102700

Ejemplares similares

The Engagement Between MDSCs and Metastases: Partners in Crime
por: Trovato, Rosalinda, et al.
Publicado: (2020)

Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression
por: Groth, Christopher, et al.
Publicado: (2018)

Immunotherapy Targeting Myeloid-Derived Suppressor Cells (MDSCs) in Tumor Microenvironment
por: Gao, Xidan, et al.
Publicado: (2021)

"Open Sesame" to the complexity of pattern recognition receptors of myeloid-derived suppressor cells in cancer
por: Wang, Tian, et al.
Publicado: (2023)

Myeloid-Derived Suppressor Cells (MDSCs) in Haematology
por: Bizymi, Nikoleta, et al.
Publicado: (2021)

Immunosuppression by monocytic myeloid-derived suppressor cells in patients with pancreatic ductal carcinoma is orchestrated by STAT3
por: Trovato, Rosalinda, et al.
Publicado: (2019)

Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies
por: Shou, Dawei, et al.
Publicado: (2016)

Myeloid Derived Suppressor Cells (MDSCs) Are Increased and Exert Immunosuppressive Activity Together with Polymorphonuclear Leukocytes (PMNs) in Chronic Myeloid Leukemia Patients
por: Giallongo, Cesarina, et al.
Publicado: (2014)

Clinical Relevance and Immunosuppressive Pattern of Circulating and Infiltrating Subsets of Myeloid-Derived Suppressor Cells (MDSCs) in Epithelial Ovarian Cancer
por: Okła, Karolina, et al.
Publicado: (2019)

New Insights into the Multifaceted Role of Myeloid-Derived Suppressor Cells (MDSCs) in High-Grade Gliomas: From Metabolic Reprograming, Immunosuppression, and Therapeutic Resistance to Current Strategies for Targeting MDSCs
por: Lakshmanachetty, Senthilnath, et al.
Publicado: (2021)

The Functional Crosstalk between Myeloid-Derived Suppressor Cells and Regulatory T Cells within the Immunosuppressive Tumor Microenvironment
por: Haist, Maximilian, et al.
Publicado: (2021)

Targeting tumour-reprogrammed myeloid cells: the new battleground in cancer immunotherapy
por: De Sanctis, Francesco, et al.
Publicado: (2022)

The Effect of Immunosuppressive Drugs on MDSCs in Transplantation
por: Yang, Fan, et al.
Publicado: (2018)

Myeloid-Derived Suppressor Cells (MDSCs) in Ovarian Cancer—Looking Back and Forward
por: Okła, Karolina
Publicado: (2023)

Gene expression profiling of human fibrocytic myeloid-derived suppressor cells (f-MDSCs)
por: Mazza, Emilia Maria Cristina, et al.
Publicado: (2014)

Re-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy
por: He, Wei, et al.
Publicado: (2016)

The Role of Myeloid-Derived Suppressor Cells (MDSCs) in the Development and/or Progression of Endometriosis-State of the Art
por: Suszczyk, Dorota, et al.
Publicado: (2021)

The Role of Myeloid-Derived Suppressor Cells (MDSCs) in Graft-versus-Host Disease (GVHD)
por: Demosthenous, Christos, et al.
Publicado: (2021)

The Emerging Immunological Role of Post-Translational Modifications by Reactive Nitrogen Species in Cancer Microenvironment
por: De Sanctis, Francesco, et al.
Publicado: (2014)

Immunotherapy of targeting MDSCs in tumor microenvironment
por: Sui, Hongshu, et al.
Publicado: (2022)

Interplay between myeloid-derived suppressor cells (MDSCs) and Th17 cells: foe or friend?
por: Wen, Liang, et al.
Publicado: (2016)

Analysis of the Expression and Regulation of PD-1 Protein on the Surface of Myeloid-Derived Suppressor Cells (MDSCs)
por: Nam, Sorim, et al.
Publicado: (2019)

Potential Role of Myeloid-Derived Suppressor Cells (MDSCs) in Age-Related Macular Degeneration (AMD)
por: Kauppinen, Anu, et al.
Publicado: (2020)

Alternative approaches to myeloid suppressor cell therapy in transplantation: comparing regulatory macrophages to tolerogenic DCs and MDSCs
por: Riquelme, Paloma, et al.
Publicado: (2012)

Crosstalk between regulatory T cells (Tregs) and myeloid derived suppressor cells (MDSCs) during melanoma growth
por: Fujimura, Taku, et al.
Publicado: (2012)

Temporal and spatial profile of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) in ischemic stroke in mice
por: Kawano, Tomohiro, et al.
Publicado: (2019)

Stroke-Induced Modulation of Myeloid-Derived Suppressor Cells (MDSCs) and IL-10-Producing Regulatory Monocytes
por: Achmus, Lennart, et al.
Publicado: (2020)

Immune checkpoint blockade therapy mitigates systemic inflammation and affects cellular FLIP-expressing monocytic myeloid-derived suppressor cells in non-progressor non-small cell lung cancer patients
por: Adamo, Annalisa, et al.
Publicado: (2023)

Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor
por: Yan, Dehong, et al.
Publicado: (2019)

Donor myeloid derived suppressor cells (MDSCs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo
por: Cai, Songjie, et al.
Publicado: (2020)

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells
por: Lee, Bo-Ra, et al.
Publicado: (2014)

Ferumoxytol Attenuates the Function of MDSCs to Ameliorate LPS-Induced Immunosuppression in Sepsis
por: Xue, Yaxian, et al.
Publicado: (2019)

Identification of granulocytic myeloid-derived suppressor cells (G-MDSCs) in the peripheral blood of Hodgkin and non-Hodgkin lymphoma patients
por: Marini, Olivia, et al.
Publicado: (2016)

Effects of vitamin D on macrophages and myeloid-derived suppressor cells (MDSCs) hyperinflammatory response in the lungs of COVID-19 patients
por: Kloc, Malgorzata, et al.
Publicado: (2021)

Early Myeloid Derived Suppressor Cells (eMDSCs) Are Associated With High Donor Myeloid Chimerism Following Haploidentical HSCT for Sickle Cell Disease
por: Bhat, Deepali K., et al.
Publicado: (2021)

MicroRNAs/LncRNAs Modulate MDSCs in Tumor Microenvironment
por: Liu, Xiaocui, et al.
Publicado: (2022)

Breaking the Immune Complexity of the Tumor Microenvironment Using Single-Cell Technologies
por: Caligola, Simone, et al.
Publicado: (2022)

Immune suppression by myeloid-derived suppressor cells, MDSCs, in MYCN-driven neuroblastoma provides a potential target for cancer immunotherapy
por: Eissler, Nina, et al.
Publicado: (2014)

Accumulation of myeloid-derived suppressor cells (MDSCs) induced by low levels of IL-6 correlates with poor prognosis in bladder cancer
por: Yang, Guoliang, et al.
Publicado: (2017)

P752: TRANSCRIPTOMIC ANALYSIS OF MYELOID-DERIVED SUPPRESSOR CELLS (MDSCS) IN THE PERIPHERAL BLOOD OF PATIENTS WITH CHRONIC IDIOPATHIC NEUTROPENIA (CIN)
por: Bizymi, Nikoleta, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3g0pbiv7hocgofjri4g81ng31q