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Cofilin and Actin Dynamics: Multiple Modes of Regulation and Their Impacts in Neuronal Development and Degeneration
Proteins of the actin depolymerizing factor (ADF)/cofilin family are ubiquitous among eukaryotes and are essential regulators of actin dynamics and function. Mammalian neurons express cofilin-1 as the major isoform, but ADF and cofilin-2 are also expressed. All isoforms bind preferentially and coope...
Autores principales: | Bamburg, James R., Minamide, Laurie S., Wiggan, O’Neil, Tahtamouni, Lubna H., Kuhn, Thomas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534876/ https://www.ncbi.nlm.nih.gov/pubmed/34685706 http://dx.doi.org/10.3390/cells10102726 |
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