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Cofilin and Actin Dynamics: Multiple Modes of Regulation and Their Impacts in Neuronal Development and Degeneration

Proteins of the actin depolymerizing factor (ADF)/cofilin family are ubiquitous among eukaryotes and are essential regulators of actin dynamics and function. Mammalian neurons express cofilin-1 as the major isoform, but ADF and cofilin-2 are also expressed. All isoforms bind preferentially and coope...

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Detalles Bibliográficos
Autores principales: Bamburg, James R., Minamide, Laurie S., Wiggan, O’Neil, Tahtamouni, Lubna H., Kuhn, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8534876/
https://www.ncbi.nlm.nih.gov/pubmed/34685706
http://dx.doi.org/10.3390/cells10102726

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