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Development of a Quantitative FMRP Assay for Mouse Tissue Applications

Fragile X syndrome results from the absence of the FMR1 gene product—Fragile X Mental Retardation Protein (FMRP). Fragile X animal research has lacked a reliable method to quantify FMRP. We report the development of an array of FMRP-specific monoclonal antibodies and their application for quantitati...

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Detalles Bibliográficos
Autores principales: Adayev, Tatyana, LaFauci, Giuseppe, Xu, Weimin, Dobkin, Carl, Kascsak, Richard, Brown, W. Ted, Goodman, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535242/
https://www.ncbi.nlm.nih.gov/pubmed/34680911
http://dx.doi.org/10.3390/genes12101516