Telomerase (hTERT) Overexpression Reveals a Promising Prognostic Biomarker and Therapeutical Target in Different Clinical Subtypes of Pediatric Acute Lymphoblastic Leukaemia

Acute Lymphoblastic Leukemia (ALL) is a neoplasm of the hematopoietic system defined as a clonal expansion of an abnormal lymphoid precursor cell. It mostly affects children under five years of age and is the most common tumor to afflict pediatric patients. The expression of the human telomerase gen...

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Detalles Bibliográficos
Autores principales: Nogueira, Beatriz Maria Dias, Pantoja, Laudreísa da Costa, da Silva, Emerson Lucena, Mello Júnior, Fernando Augusto Rodrigues, Teixeira, Eliel Barbosa, Wanderley, Alayde Vieira, Maués, Jersey Heitor da Silva, Filho, Manoel Odorico de Moraes, de Moraes, Maria Elisabete Amaral, Montenegro, Raquel Carvalho, Khayat, André Salim, Moreira-Nunes, Caroline Aquino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535500/
https://www.ncbi.nlm.nih.gov/pubmed/34681025
http://dx.doi.org/10.3390/genes12101632

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