Context Fear Conditioning in Down Syndrome Mouse Models: Effects of Trisomic Gene Content, Age, Sex and Genetic Background

Down syndrome (DS), trisomy of the long arm of human chromosome 21 (Hsa21), is the most common genetic cause of intellectual disability (ID). Currently, there are no effective pharmacotherapies. The success of clinical trials to improve cognition depends in part on the design of preclinical evaluati...

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Detalles Bibliográficos
Autores principales: Ahmed, Md. Mahiuddin, Block, Aaron, Busquet, Nicolas, Gardiner, Katheleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535510/
https://www.ncbi.nlm.nih.gov/pubmed/34680922
http://dx.doi.org/10.3390/genes12101528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535510/
https://www.ncbi.nlm.nih.gov/pubmed/34680922
http://dx.doi.org/10.3390/genes12101528

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