Cargando…

Mechanism of Phosgene-Induced Acute Lung Injury and Treatment Strategy

Phosgene (COCl(2)) was once used as a classic suffocation poison and currently plays an essential role in industrial production. Due to its high toxicity, the problem of poisoning caused by leakage during production, storage, and use cannot be ignored. Phosgene mainly acts on the lungs, causing long...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Qianying, Huang, Siyu, Meng, Xiangyan, Zhang, Jianfeng, Yu, Sifan, Li, Junfeng, Shi, Mingyu, Fan, Haojun, Zhao, Yanmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535529/ https://www.ncbi.nlm.nih.gov/pubmed/34681591 http://dx.doi.org/10.3390/ijms222010933

Ejemplares similares

MicroRNAs: Important Regulatory Molecules in Acute Lung Injury/Acute Respiratory Distress Syndrome
por: Lu, Qianying, et al.
Publicado: (2022)

Identification of potentially functional circRNAs and prediction of the circRNA-miRNA-hub gene network in mice with primary blast lung injury
por: Lu, Qianying, et al.
Publicado: (2023)

Phosgene-Induced acute lung injury: Approaches for mechanism-based treatment strategies
por: Cao, Chao, et al.
Publicado: (2022)

Acute Lung Injury after Phosgene Inhalation
por: Lim, Sung-Chul, et al.
Publicado: (1996)

Crosstalk between Inflammation and Hemorrhage/Coagulation Disorders in Primary Blast Lung Injury
por: Li, Junfeng, et al.
Publicado: (2023)

miR-223: a key regulator of pulmonary inflammation
por: Shi, Mingyu, et al.
Publicado: (2023)

Phosgene Gas
Publicado: (1899)

The Role of Long Noncoding RNAs in Intestinal Health and Diseases: A Focus on the Intestinal Barrier
por: Lu, Qianying, et al.
Publicado: (2023)

Accidental inhalation injury of phosgene gas leading to acute respiratory distress syndrome
por: Kumar, Anand, et al.
Publicado: (2012)

NEDD4 attenuates phosgene‐induced acute lung injury through the inhibition of Notch1 activation
por: Shao, Yiru, et al.
Publicado: (2022)

Hepatic Cirrhosis Following Phosgene Poisoning
por: Cruickshank, J. N.
Publicado: (1925)

Novel synthetic pathway for the production of phosgene
por: Voßnacker, Patrick, et al.
Publicado: (2021)

Phosgene-induced acute lung injury (ALI): differences from chlorine-induced ALI and attempts to translate toxicology to clinical medicine
por: Li, Wenli, et al.
Publicado: (2017)

Comprehensive Analysis of the Profiles of Differentially Expressed mRNAs, lncRNAs, and circRNAs in Phosgene-Induced Acute Lung Injury
por: Shao, Yiru, et al.
Publicado: (2021)

RGD-Hydrogel Improves the Therapeutic Effect of Bone Marrow-Derived Mesenchymal Stem Cells on Phosgene-Induced Acute Lung Injury in Rats
por: Ding, Jianwen, et al.
Publicado: (2022)

An amino-substituted 2-(2′-hydroxyphenyl)benzimidazole for the fluorescent detection of phosgene based on an ESIPT mechanism
por: Li, Zi-Jie, et al.
Publicado: (2021)

Phosgene Synthesis Catalysis: The Influence of Small Quantities of Bromine in the Chlorine Feedstream
por: Rossi, Giovanni E., et al.
Publicado: (2021)

Accidental Phosgene Poisoning: A Case Report and Short Review of Management
por: TY, Sri Hari, et al.
Publicado: (2023)

Accidental phosgene gas exposure: A review with background study of 10 cases
por: Vaish, Arvind Kumar, et al.
Publicado: (2013)

A Theoretical Study on the Phosgenation of 2,4-Toluenediamine (2,4-TDA)
por: Thangaraj, Ravikumar, et al.
Publicado: (2022)

Selectively Light-up Detection of Phosgene with an Aggregation-Induced Emission-Based Fluorescent Sensor
por: Cheng, Ke, et al.
Publicado: (2019)

Photo-on-Demand Phosgenation Reactions with Chloroform for Selective Syntheses of N-Substituted Ureas and Isocyanates
por: Muranaka, Ryo, et al.
Publicado: (2022)

A Rapid, Highly Sensitive and Selective Phosgene Sensor Based on 5,6‐Pinenepyridine
por: Solea, Atena B., et al.
Publicado: (2022)

Comparative Study of Phosgene Gas Sensing Using Carbon and Boron Nitride Nanomaterials—A DFT Approach
por: Kweitsu, Emmanuel Obroni, et al.
Publicado: (2020)

Metal-Decorated Phthalocyanine Monolayer as a Potential Gas Sensing Material for Phosgene: A First-Principles Study
por: Wang, Chen, et al.
Publicado: (2022)

Chronic Low-dose Exposure to Highly Toxic Gas Phosgene and Its Effect on Peak Expiratory Flow Rate
por: Tiwari, Rajnarayan R., et al.
Publicado: (2022)

Adsorption of Phosgene Gas on Pristine and Copper-Decorated B(12)N(12) Nanocages: A Comparative DFT Study
por: Hussain, Shahid, et al.
Publicado: (2020)

Photo-on-Demand In Situ Phosgenation Reactions That Cross Three Phases of a Heterogeneous Solution of Chloroform and Aqueous NaOH
por: Tsuda, Akihiko, et al.
Publicado: (2023)

Pattern Recognition Receptor–Dependent Mechanisms of Acute Lung Injury
por: Xiang, Meng, et al.
Publicado: (2010)

Deciphering the electrochemical sensing capability of novel Ga(12)As(12) nanocluster towards chemical warfare phosgene gas: insights from DFT
por: Javed, Muhammad, et al.
Publicado: (2023)

Elucidation of the Mechanism of Action of Ginseng Against Acute Lung Injury/Acute Respiratory Distress Syndrome by a Network Pharmacology-Based Strategy
por: Ding, Qi, et al.
Publicado: (2021)

Lung-Targeted Delivery of Cepharanthine by an Erythrocyte-Anchoring Strategy for the Treatment of Acute Lung Injury
por: Zheng, Jinpeng, et al.
Publicado: (2022)

Therapeutic Effect of Intravenous Infusion of Perfluorocarbon Emulsion on LPS-Induced Acute Lung Injury in Rats
por: Hou, Shike, et al.
Publicado: (2014)

Activation of multiple Toll-like receptors serves different roles in sepsis-induced acute lung injury
por: Chen, Xinlei, et al.
Publicado: (2019)

Mechanisms of Acute Lung Injury and Repair
por: Doerschug, Kevin C., et al.
Publicado: (2008)

Mesenchymal stem cells activate Notch signaling to induce regulatory dendritic cells in LPS-induced acute lung injury
por: Lu, Zhonghua, et al.
Publicado: (2020)

Open lung strategies in patients with intracranial lesions and acute lung injury
por: Wolf, S, et al.
Publicado: (2000)

Shear-induced acquired von Willebrand syndrome: an accomplice of bleeding events in adults on extracorporeal membrane oxygenation support
por: Wang, Haiwang, et al.
Publicado: (2023)

A Comprehensive Network Pharmacology-Based Strategy to Investigate Multiple Mechanisms of HeChan Tablet on Lung Cancer
por: Zhuang, Zhenjie, et al.
Publicado: (2020)

Major signaling pathways and key mediators of macrophages in acute kidney injury
por: Li, Ning, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s46lr9sl8ieie2qhaq0kldvm13