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Isorhamnetin Promotes 53BP1 Recruitment through the Enhancement of ATM Phosphorylation and Protects Mice from Radiation Gastrointestinal Syndrome

Flavonoids are a subclass of polyphenols which are attractive, due to possessing various physiological activities, including a radioprotective effect. Tumor suppressor p53 is a primary regulator in the radiation response and is involved in the pathogenesis of radiation injuries. In this study, we re...

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Detalles Bibliográficos
Autores principales: Nishiyama, Yuichi, Morita, Akinori, Tatsuta, Shogo, Kanamaru, Misaki, Sakaue, Masahiro, Ueda, Kenta, Shono, Manami, Fujita, Rie, Wang, Bing, Hosoi, Yoshio, Aoki, Shin, Sugai, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535534/
https://www.ncbi.nlm.nih.gov/pubmed/34680909
http://dx.doi.org/10.3390/genes12101514